C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: follistatin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000134363 FST 9606 + 5:53480409-53487134 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000256759 FST-001 53480409-53487134 protein_coding
  ENST00000396947 FST-003 53480626-53487106 protein_coding
  ENST00000491717 FST-002 53482694-53484111 retained_intron
  ENST00000497789 FST-005 53484216-53486092 protein_coding
  ENST00000504226 FST-004 53483611-53486090 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000256759ENST00000396947ENST00000491717ENST00000497789ENST00000504226
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000256759 4.419±0.00 4.044±0.00 0.065±0.04 1.121±0.00 7.927±0.00 0.494±0.44 0.723±0.00 0.621±0.00 0.912±0.47 0.262±0.13 2.539±1.89 4.309±2.12 5.736±0.00
ENST00000396947 N/A N/A 0.103±0.00 0.585±0.13 1.603±0.00 0.560±0.00 0.109±0.00 N/A N/A N/A 0.465±0.00 2.000±0.47 2.437±1.42
ENST00000491717 N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.624±0.00 3.446±0.00 19.115±0.00 N/A
ENST00000497789 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.507±0.00 N/A N/A
ENST00000504226 4.359±0.00 5.702±0.00 N/A 4.231±0.00 0.257±0.00 1.402±0.08 1.488±0.00 4.385±2.03 4.000±0.00 2.268±0.00 1.526±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007G2 CIL_0007G2_0002 CGP 5:53095679-53487134

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0001501 IEA skeletal system development
GO:0002244 IDA hematopoietic progenitor cell differentiation
GO:0004871 NAS signal transducer activity
GO:0005515 IPI:IEA protein binding
GO:0005576 TAS extracellular region
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0007276 IEA gamete generation
GO:0007389 IEA pattern specification process
GO:0008585 IEA female gonad development
GO:0030509 IEA BMP signaling pathway
GO:0031069 IEA hair follicle morphogenesis
GO:0032926 IDA negative regulation of activin receptor signaling pathway
GO:0042475 IEA odontogenesis of dentin-containing tooth
GO:0043395 IEA heparan sulfate proteoglycan binding
GO:0043616 IEA keratinocyte proliferation
GO:0045596 IEA negative regulation of cell differentiation
GO:0048185 IPI activin binding
GO:0051798 IDA positive regulation of hair follicle development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000052846 fsta follistatin a protein_coding Danio_rerio
ENSDARG00000057992 fstb follistatin b protein_coding Danio_rerio
ENSMUSG00000021765 Fst follistatin protein_coding Mus_musculus

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