C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: histamine receptor H4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000134489 HRH4 9606 + 18:24460629-24479957 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000256906 HRH4-001 24460629-24479957 protein_coding
  ENST00000426880 HRH4-002 24460729-24477562 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryTestisENST00000256906ENST00000426880
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Testis
ENST00000256906 0.030±0.00 0.060±0.00 0.036±0.00 0.130±0.00 0.057±0.02 0.038±0.02 0.064±0.00 0.095±0.04 0.023±0.01 0.015±0.00 0.015±0.00 0.096±0.03
ENST00000426880 N/A N/A N/A N/A 0.740±0.00 N/A N/A N/A N/A N/A 0.063±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008X5 CIL_0008X5_0001 VISTA 18:24259953-24861227
CIL_00091V CIL_00091V_0001 VISTA 18:24356022-24957424
CIL_0005WQ CIL_0005WQ_0001 CGP 18:24426616-24479957
CIL_0000RB CIL_0000RB_0001 CGP 18:24460629-25352190

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004930 IEA G-protein coupled receptor activity
GO:0004969 NAS histamine receptor activity
GO:0005886 TAS plasma membrane
GO:0006954 IEA inflammatory response
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007204 IEA positive regulation of cytosolic calcium ion concentration
GO:0008150 ND biological_process
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0043408 IEA regulation of MAPK cascade

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000045137 HRH4 (1 of 2) histamine receptor H4 protein_coding Danio_rerio
ENSDARG00000060458 HRH4 (2 of 2) histamine receptor H4 protein_coding Danio_rerio
ENSMUSG00000037346 Hrh4 histamine receptor H4 protein_coding Mus_musculus

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