C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: v-ets avian erythroblastosis virus E26 oncogene homolog 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000134954 ETS1 9606 - 11:128458761-128587558 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000319397 ETS1-003 128461766-128522304 protein_coding
  ENST00000392668 ETS1-002 128458765-128587558 protein_coding
  ENST00000525404 ETS1-007 128536412-128587542 processed_transcript
  ENST00000526145 ETS1-006 128460244-128522201 protein_coding
  ENST00000527676 ETS1-008 128571808-128587523 processed_transcript
  ENST00000530924 ETS1-009 128462544-128463950 retained_intron
  ENST00000531611 ETS1-005 128461494-128522264 protein_coding
  ENST00000535549 ETS1-201 128458761-128522310 protein_coding
  ENST00000608978 ETS1-010 128489470-128505394 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryTestisENST00000392668ENST00000526145ENST00000535549
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Testis
ENST00000392668 N/A 9.691±0.00 2.910±0.00 N/A 2.920±1.22 N/A 5.513±0.00 2.920±0.28 1.099±0.00 15.239±0.00 0.571±0.00 1.098±0.14 N/A
ENST00000526145 N/A N/A N/A N/A 2.294±0.00 4.073±0.00 1.113±0.00 1.309±0.00 3.355±0.00 7.572±0.00 1.348±0.58 2.916±0.00 N/A
ENST00000535549 70.642±0.00 37.576±0.00 N/A 2.162±0.00 15.940±0.00 20.280±0.00 4.625±0.00 7.130±0.00 N/A 39.313±0.00 N/A 2.661±0.00 8.655±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00050Y CIL_00050Y_0002 CGP 11:126423359-128587558
CIL_00050X CIL_00050X_0002 CGP 11:128458761-128813267

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000981 IBA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001666 IEA response to hypoxia
GO:0003677 ISS DNA binding
GO:0003700 IDA:IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IEA:IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005667 IEA transcription factor complex
GO:0005737 IDA cytoplasm
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0006366 IBA transcription from RNA polymerase II promoter
GO:0006955 TAS immune response
GO:0007565 IEA female pregnancy
GO:0008134 NAS transcription factor binding
GO:0008284 IEA positive regulation of cell proliferation
GO:0008285 TAS negative regulation of cell proliferation
GO:0009611 IEA response to wounding
GO:0009612 IEA response to mechanical stimulus
GO:0010595 IMP positive regulation of endothelial cell migration
GO:0010715 IEA regulation of extracellular matrix disassembly
GO:0021854 IEA hypothalamus development
GO:0021983 IEA pituitary gland development
GO:0030335 IEA positive regulation of cell migration
GO:0030578 IDA PML body organization
GO:0032355 IEA response to estradiol
GO:0034616 IEA response to laminar fluid shear stress
GO:0035035 IEA histone acetyltransferase binding
GO:0042981 IDA regulation of apoptotic process
GO:0043565 IEA sequence-specific DNA binding
GO:0045171 IDA intercellular bridge
GO:0045648 IDA positive regulation of erythrocyte differentiation
GO:0045765 IMP regulation of angiogenesis
GO:0045766 IEA positive regulation of angiogenesis
GO:0045786 IMP negative regulation of cell cycle
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046677 IDA response to antibiotic
GO:0048870 IMP cell motility
GO:0051272 IMP positive regulation of cellular component movement
GO:0060055 IEA angiogenesis involved in wound healing
GO:0060206 IEA estrous cycle phase
GO:0070301 IEA cellular response to hydrogen peroxide
GO:0070555 IEA response to interleukin-1

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000024431 ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 protein_coding Danio_rerio
ENSMUSG00000032035 Ets1 E26 avian leukemia oncogene 1, 5' domain protein_coding Mus_musculus

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