C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SRSF protein kinase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000135250 SRPK2 9606 - 7:105110704-105399308 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000357311 SRPK2-001 105116377-105269015 protein_coding
  ENST00000393651 SRPK2-008 105116376-105388894 protein_coding
  ENST00000460391 SRPK2-013 105167377-105388894 protein_coding
  ENST00000462282 SRPK2-010 105203627-105399308 processed_transcript
  ENST00000465072 SRPK2-003 105115269-105132793 nonsense_mediated_decay
  ENST00000465112 SRPK2-009 105203694-105388898 nonsense_mediated_decay
  ENST00000466917 SRPK2-004 105117296-105144066 retained_intron
  ENST00000474770 SRPK2-006 105117580-105133068 protein_coding
  ENST00000476117 SRPK2-012 105160301-105203732 retained_intron
  ENST00000477925 SRPK2-007 105117388-105142336 protein_coding
  ENST00000482862 SRPK2-015 105203723-105389390 processed_transcript
  ENST00000482897 SRPK2-014 105160545-105389391 protein_coding
  ENST00000485455 SRPK2-011 105117349-105203656 processed_transcript
  ENST00000489828 SRPK2-002 105117526-105298779 protein_coding
  ENST00000493638 SRPK2-005 105110704-105117479 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000357311ENST00000393651ENST00000466917ENST00000489828
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000357311 N/A N/A N/A 21.590±0.00 N/A 5.819±0.00 N/A N/A N/A 10.203±0.00 3.343±0.00 N/A N/A N/A
ENST00000393651 7.508±0.00 6.691±0.00 3.736±0.00 39.284±0.00 6.441±0.34 7.131±0.00 4.523±0.00 3.211±0.67 6.367±3.40 7.763±0.00 N/A 9.075±1.60 5.057±1.00 33.931±11.16
ENST00000466917 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.245±0.00 N/A N/A N/A
ENST00000489828 N/A N/A N/A 10.740±0.00 N/A N/A 2.541±0.00 N/A N/A N/A N/A N/A 9.094±0.00 67.144±46.97

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005BG CIL_0005BG_0002 CGP 7:104328656-105114361
CIL_00040Y CIL_00040Y_0001 CGP 7:105014179-105399308
CIL_0005BH CIL_0005BH_0002 CGP 7:105110704-105522267

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000245 IDA spliceosomal complex assembly
GO:0000287 IDA magnesium ion binding
GO:0001525 ISS angiogenesis
GO:0004672 IEA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA:IDA ATP binding
GO:0005634 IDA nucleus
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0006468 IEA:IDA protein phosphorylation
GO:0008152 IEA metabolic process
GO:0008284 IDA positive regulation of cell proliferation
GO:0008380 IDA RNA splicing
GO:0010628 ISS positive regulation of gene expression
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0030154 IEA cell differentiation
GO:0035063 ISS nuclear speck organization
GO:0035556 IDA intracellular signal transduction
GO:0043525 ISS positive regulation of neuron apoptotic process
GO:0044822 IDA poly(A) RNA binding
GO:0045070 IDA positive regulation of viral genome replication
GO:0045071 IDA negative regulation of viral genome replication
GO:0045087 IC innate immune response
GO:0045787 ISS positive regulation of cell cycle
GO:0048024 TAS regulation of mRNA splicing, via spliceosome
GO:0071889 ISS 14-3-3 protein binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000029368 SRPK2 SRSF protein kinase 2 protein_coding Danio_rerio
ENSMUSG00000062604 Srpk2 serine/arginine-rich protein specific kinase 2 protein_coding Mus_musculus

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