C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: MyoD family inhibitor domain containing
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000135272 MDFIC 9606 + 7:114922154-115019916 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000257724 MDFIC-007 114922154-115019202 protein_coding
  ENST00000393486 MDFIC-001 114922359-115019202 protein_coding
  ENST00000423503 MDFIC-002 114922854-114923658 protein_coding
  ENST00000427207 MDFIC-004 114923076-114980084 protein_coding
  ENST00000431629 MDFIC-005 114923064-115015961 nonsense_mediated_decay
  ENST00000448022 MDFIC-003 114922561-114923665 protein_coding
  ENST00000498196 MDFIC-006 114933869-115015765 protein_coding
  ENST00000614186 MDFIC-201 114922154-115019916 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000257724ENST00000393486ENST00000431629ENST00000614186
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000257724 3.102±0.00 N/A 0.335±0.00 0.311±0.00 N/A 0.977±0.00 1.303±0.41 1.263±0.00 3.751±0.00 2.249±0.00 0.455±0.00 1.527±0.76 2.291±0.44 0.419±0.00
ENST00000393486 10.429±0.00 9.980±0.00 0.322±0.00 0.823±0.02 11.044±4.61 3.781±0.96 1.998±0.96 4.099±0.00 2.260±0.04 4.884±0.30 0.910±0.15 1.097±0.62 2.033±0.59 2.247±0.00
ENST00000431629 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.163±0.00 1.004±0.00 7.519±0.00 1.000±0.00
ENST00000614186 2.068±0.00 N/A N/A 0.365±0.00 5.848±0.00 1.319±0.46 0.902±0.42 1.706±0.00 1.222±0.53 2.244±0.00 0.300±0.00 0.615±0.34 0.637±0.10 0.546±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000411 CIL_000411_0001 CGP 7:114086327-115019916
CIL_0007K6 CIL_0007K6_0001 UCNEbase 7:114130894-114986758
CIL_0007XI CIL_0007XI_0001 VISTA 7:114321018-114923034
CIL_0008GN CIL_0008GN_0001 VISTA 7:114347932-114950502
CIL_00094C CIL_00094C_0001 VISTA 7:114352845-114953917
CIL_0008AV CIL_0008AV_0001 VISTA 7:114355054-114956318
CIL_0008GL CIL_0008GL_0001 VISTA 7:114359656-114962023
CIL_0008OY CIL_0008OY_0001 VISTA 7:114386857-114989717
CIL_000814 CIL_000814_0001 VISTA 7:114441498-115042782
CIL_000894 CIL_000894_0001 VISTA 7:114455115-115056536
CIL_00094G CIL_00094G_0001 VISTA 7:114523742-115124407
CIL_000410 CIL_000410_0001 CGP 7:114922154-116159896

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001522 IEA pseudouridine synthesis
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0005794 IDA Golgi apparatus
GO:0006351 IEA transcription, DNA-templated
GO:0007257 IDA activation of JUN kinase activity
GO:0008134 IPI transcription factor binding
GO:0016032 IEA viral process
GO:0030111 IDA regulation of Wnt signaling pathway
GO:0030332 IPI cyclin binding
GO:0030515 IEA snoRNA binding
GO:0030957 IDA Tat protein binding
GO:0042254 IEA ribosome biogenesis
GO:0042308 ISS negative regulation of protein import into nucleus
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0050434 IDA positive regulation of viral transcription
GO:0072588 IEA box H/ACA RNP complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074223 MDFIC (1 of 2) MyoD family inhibitor domain containing protein_coding Danio_rerio
ENSDARG00000095284 MDFIC (2 of 2) MyoD family inhibitor domain containing protein_coding Danio_rerio
ENSMUSG00000041390 Mdfic MyoD family inhibitor domain containing protein_coding Mus_musculus

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