C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: 5'-nucleotidase, ecto (CD73)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000135318 NT5E 9606 + 6:85449584-85495791 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000257770 NT5E-001 85450091-85495778 protein_coding
  ENST00000369646 NT5E-002 85450091-85471599 protein_coding
  ENST00000369651 NT5E-201 85449584-85495791 protein_coding
  ENST00000416334 NT5E-003 85471381-85492161 protein_coding
  ENST00000437581 NT5E-004 85485397-85491325 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000257770ENST00000369646ENST00000369651ENST00000416334
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000257770 9.870±0.00 9.598±0.00 0.897±0.00 2.445±0.12 5.257±0.66 6.907±3.45 1.151±0.74 6.071±2.28 6.442±0.89 1.856±0.73 0.659±0.23 7.980±5.61 14.792±5.45 5.535±1.35
ENST00000369646 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.245±0.00 N/A N/A N/A
ENST00000369651 N/A N/A N/A N/A N/A 1.057±0.40 N/A N/A N/A 0.870±0.29 N/A N/A N/A 1.001±0.00
ENST00000416334 N/A N/A N/A N/A N/A N/A 0.730±0.00 N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007K0 CIL_0007K0_0001 UCNEbase 6:84361462-85614404
CIL_00066W CIL_00066W_0001 CGP 6:84687351-85495791
CIL_0008Z9 CIL_0008Z9_0001 VISTA 6:84885897-85488288
CIL_0007TL CIL_0007TL_0001 VISTA 6:84971170-85574346
CIL_0006BN CIL_0006BN_0002 CGP 6:85449584-85594156

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0006144 TAS purine nucleobase metabolic process
GO:0006195 TAS purine nucleotide catabolic process
GO:0006196 IEA AMP catabolic process
GO:0006206 TAS pyrimidine nucleobase metabolic process
GO:0006259 TAS DNA metabolic process
GO:0008253 EXP 5'-nucleotidase activity
GO:0009166 IEA nucleotide catabolic process
GO:0009986 IDA cell surface
GO:0016020 TAS membrane
GO:0016311 IEA dephosphorylation
GO:0016787 IEA hydrolase activity
GO:0016788 IEA hydrolase activity, acting on ester bonds
GO:0031225 IEA anchored component of membrane
GO:0044281 TAS small molecule metabolic process
GO:0046086 IEA adenosine biosynthetic process
GO:0046135 TAS pyrimidine nucleoside catabolic process
GO:0046872 IEA metal ion binding
GO:0050728 IEA negative regulation of inflammatory response
GO:0055086 TAS nucleobase-containing small molecule metabolic process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000071017 nt5e 5'-nucleotidase, ecto (CD73) protein_coding Danio_rerio
ENSMUSG00000032420 Nt5e 5' nucleotidase, ecto protein_coding Mus_musculus

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