C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: growth differentiation factor 11
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000135414 GDF11 9606 + 12:55743280-55757278 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000257868 GDF11-001 55743280-55757278 protein_coding
  ENST00000546799 GDF11-002 55743399-55757127 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryENST00000257868
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary
ENST00000257868 3.772±0.00 0.520±0.00 1.973±1.20 0.863±0.00 2.026±0.78 1.624±1.24 0.314±0.00 0.781±0.00 2.547±0.00 0.423±0.00 5.177±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001501 TAS skeletal system development
GO:0001656 IEA metanephros development
GO:0001657 IEA ureteric bud development
GO:0005125 IEA cytokine activity
GO:0005515 IEA protein binding
GO:0005575 ND cellular_component
GO:0005615 IEA extracellular space
GO:0007399 TAS nervous system development
GO:0007498 TAS mesoderm development
GO:0008083 IEA growth factor activity
GO:0008285 IEA negative regulation of cell proliferation
GO:0009887 IEA organ morphogenesis
GO:0009952 IEA anterior/posterior pattern specification
GO:0021512 IEA spinal cord anterior/posterior patterning
GO:0031016 IEA pancreas development
GO:0040007 IEA growth
GO:0043234 IPI protein complex
GO:0045596 IEA negative regulation of cell differentiation
GO:0048469 IEA cell maturation
GO:0048593 IEA camera-type eye morphogenesis
GO:0060021 IEA palate development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044924 gdf11 growth differentiation factor 11 protein_coding Danio_rerio
ENSMUSG00000025352 Gdf11 growth differentiation factor 11 protein_coding Mus_musculus

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