C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glutaminase 2 (liver, mitochondrial)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000135423 GLS2 9606 - 12:56470944-56488414 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000311966 GLS2-001 56470952-56488397 protein_coding
  ENST00000390288 GLS2-007 56470952-56472472 retained_intron
  ENST00000424141 GLS2-002 56470952-56488129 nonsense_mediated_decay
  ENST00000461077 GLS2-010 56475054-56488132 protein_coding
  ENST00000471282 GLS2-011 56479569-56488362 retained_intron
  ENST00000476991 GLS2-014 56473565-56476993 processed_transcript
  ENST00000479952 GLS2-006 56470952-56488152 nonsense_mediated_decay
  ENST00000483347 GLS2-008 56478195-56488414 nonsense_mediated_decay
  ENST00000486433 GLS2-003 56470954-56488397 nonsense_mediated_decay
  ENST00000486896 GLS2-005 56474691-56488249 nonsense_mediated_decay
  ENST00000491880 GLS2-012 56479593-56487599 retained_intron
  ENST00000494345 GLS2-004 56475822-56488359 retained_intron
  ENST00000494474 GLS2-009 56474855-56488368 nonsense_mediated_decay
  ENST00000496006 GLS2-013 56474406-56477700 retained_intron
  ENST00000539272 GLS2-201 56470944-56480458 protein_coding
  ENST00000610413 GLS2-202 56470944-56488414 protein_coding
  ENST00000623608 GLS2-203 56470944-56488414 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainKidneyLiverLungOvaryENST00000311966ENST00000390288ENST00000424141ENST00000479952ENST00000496006ENST00000610413ENST00000623608
Transcript ID Brain Kidney Liver Lung Ovary
ENST00000311966 2.411±0.00 22.732±0.00 N/A N/A N/A
ENST00000390288 N/A N/A 0.561±0.00 0.593±0.00 N/A
ENST00000424141 3.900±0.00 N/A 19.504±0.00 N/A N/A
ENST00000479952 1.894±0.00 N/A N/A N/A N/A
ENST00000496006 N/A N/A N/A N/A 1.670±0.00
ENST00000610413 1.538±0.00 N/A N/A N/A N/A
ENST00000623608 N/A 6.896±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002KT CIL_0002KT_0002 CGP 12:56468567-56488414

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004359 IEA glutaminase activity
GO:0005515 IPI:IEA protein binding
GO:0005739 IDA mitochondrion
GO:0005759 TAS mitochondrial matrix
GO:0006520 TAS cellular amino acid metabolic process
GO:0006541 IEA glutamine metabolic process
GO:0007268 TAS synaptic transmission
GO:0007269 TAS neurotransmitter secretion
GO:0008652 TAS cellular amino acid biosynthetic process
GO:0014047 TAS glutamate secretion
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0042981 IMP regulation of apoptotic process
GO:0044281 TAS small molecule metabolic process
GO:0072593 IMP reactive oxygen species metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000002917 GLS2 (1 of 2) glutaminase 2 (liver, mitochondrial) protein_coding Danio_rerio
ENSDARG00000069095 gls2 glutaminase 2 (liver, mitochondrial) protein_coding Danio_rerio
ENSMUSG00000044005 Gls2 glutaminase 2 (liver, mitochondrial) protein_coding Mus_musculus

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