C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: extra spindle pole bodies homolog 1 (S. cerevisiae)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000135476 ESPL1 9606 + 12:53268299-53293643 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000257934 ESPL1-201 53268299-53293643 protein_coding
  ENST00000535123 ESPL1-008 53279705-53288324 retained_intron
  ENST00000549154 ESPL1-003 53287256-53293635 retained_intron
  ENST00000550026 ESPL1-004 53274081-53274952 processed_transcript
  ENST00000552462 ESPL1-002 53268335-53293474 protein_coding
  ENST00000552600 ESPL1-006 53287881-53289460 retained_intron
  ENST00000552671 ESPL1-001 53268333-53293638 nonsense_mediated_decay
  ENST00000553016 ESPL1-005 53282250-53289295 retained_intron
  ENST00000553219 ESPL1-007 53268299-53269565 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonHeartLiverLungMuscleOvaryPlacentaTestisENST00000257934ENST00000535123ENST00000549154ENST00000550026ENST00000552462ENST00000552600ENST00000552671ENST00000553016ENST00000553219
Transcript ID Bladder Brain Breast Colon Heart Liver Lung Muscle Ovary Placenta Testis
ENST00000257934 N/A N/A N/A 0.164±0.00 N/A N/A 0.100±0.00 N/A 1.059±1.11 0.548±0.14 0.657±0.00
ENST00000535123 1.638±0.00 N/A N/A N/A N/A 0.105±0.00 0.169±0.00 N/A N/A N/A N/A
ENST00000549154 0.189±0.00 0.061±0.00 0.079±0.00 N/A 0.059±0.00 N/A N/A 0.012±0.00 N/A 0.403±0.00 3.325±0.00
ENST00000550026 N/A 0.074±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000552462 N/A N/A N/A N/A N/A 0.021±0.00 N/A N/A 2.409±0.00 0.733±0.00 3.690±2.51
ENST00000552600 N/A N/A 0.613±0.00 0.805±0.00 N/A N/A N/A N/A 7.886±0.00 2.596±0.00 13.800±0.00
ENST00000552671 N/A N/A 0.171±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000553016 N/A N/A N/A N/A 0.053±0.00 N/A N/A N/A N/A N/A N/A
ENST00000553219 N/A N/A N/A 1.557±0.00 N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001QS CIL_0001QS_0001 CGP 12:53251251-53293643
CIL_0001IH CIL_0001IH_0001 CGP 12:53268299-53299450

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000070 IMP mitotic sister chromatid segregation
GO:0000212 IEA meiotic spindle organization
GO:0000278 TAS mitotic cell cycle
GO:0000910 NAS cytokinesis
GO:0003824 NAS catalytic activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005813 IDA centrosome
GO:0005829 TAS cytosol
GO:0006508 IEA proteolysis
GO:0006915 TAS apoptotic process
GO:0007059 IEA chromosome segregation
GO:0007067 IEA mitotic nuclear division
GO:0007127 IEA meiosis I
GO:0008233 IEA peptidase activity
GO:0008234 NAS cysteine-type peptidase activity
GO:0040001 NAS establishment of mitotic spindle localization
GO:0045143 IEA homologous chromosome segregation
GO:0045842 NAS positive regulation of mitotic metaphase/anaphase transition
GO:0045875 NAS negative regulation of sister chromatid cohesion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075354 espl1 extra spindle poles like 1 protein_coding Danio_rerio
ENSMUSG00000058290 Espl1 extra spindle pole bodies 1 (S. cerevisiae) protein_coding Mus_musculus

Loading