C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: endothelin receptor type B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000136160 EDNRB 9606 - 13:77895481-77919768 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000334286 EDNRB-003 77895489-77918810 protein_coding
  ENST00000377211 EDNRB-001 77895481-77919768 protein_coding
  ENST00000475537 EDNRB-002 77918339-77919363 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000334286ENST00000377211
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000334286 59.199±0.00 12.270±0.00 3.993±0.00 8.983±0.02 7.449±2.90 11.479±7.79 6.253±4.40 22.114±15.83 5.567±1.04 21.549±8.73 2.282±0.00 1.509±0.31 22.554±7.94 4.335±0.00
ENST00000377211 N/A 1.740±0.00 N/A N/A N/A 3.426±0.00 N/A N/A 0.864±0.00 N/A 0.474±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00086M CIL_00086M_0001 VISTA 13:77531993-78133579
CIL_00004C CIL_00004C_0001 CGP 13:77697854-77919768
CIL_0000U0 CIL_0000U0_0001 CGP 13:77895481-78603560

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0001755 IEA neural crest cell migration
GO:0001934 IEA positive regulation of protein phosphorylation
GO:0004930 IEA G-protein coupled receptor activity
GO:0004962 IDA endothelin receptor activity
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006885 IEA regulation of pH
GO:0007166 TAS cell surface receptor signaling pathway
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007194 TAS negative regulation of adenylate cyclase activity
GO:0007200 IEA phospholipase C-activating G-protein coupled receptor signaling pathway
GO:0007204 IEA positive regulation of cytosolic calcium ion concentration
GO:0007399 TAS nervous system development
GO:0007422 IEA peripheral nervous system development
GO:0007497 IEA posterior midgut development
GO:0007568 IEA aging
GO:0008217 IEA regulation of blood pressure
GO:0008284 IEA positive regulation of cell proliferation
GO:0014043 ISS negative regulation of neuron maturation
GO:0014070 IEA response to organic cyclic compound
GO:0014826 IMP vein smooth muscle contraction
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0017046 IPI peptide hormone binding
GO:0019233 IEA sensory perception of pain
GO:0019934 IEA cGMP-mediated signaling
GO:0030318 IEA melanocyte differentiation
GO:0031620 IEA regulation of fever generation
GO:0031702 IEA type 1 angiotensin receptor binding
GO:0031965 IEA nuclear membrane
GO:0032269 IMP negative regulation of cellular protein metabolic process
GO:0032496 IEA response to lipopolysaccharide
GO:0035645 ISS enteric smooth muscle cell differentiation
GO:0035810 IEA positive regulation of urine volume
GO:0035815 IEA positive regulation of renal sodium excretion
GO:0042045 IEA epithelial fluid transport
GO:0042310 IMP vasoconstriction
GO:0042311 IEA vasodilation
GO:0043066 IEA negative regulation of apoptotic process
GO:0043473 IEA pigmentation
GO:0045121 IEA membrane raft
GO:0048066 IEA developmental pigmentation
GO:0048246 IMP macrophage chemotaxis
GO:0048265 IEA response to pain
GO:0048484 ISS enteric nervous system development
GO:0050678 IEA regulation of epithelial cell proliferation
GO:0051930 IEA regulation of sensory perception of pain
GO:0060406 IEA positive regulation of penile erection
GO:0071222 IEA cellular response to lipopolysaccharide
GO:0086100 IEA endothelin receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000089334 ednrb1a endothelin receptor B1a protein_coding Danio_rerio
ENSMUSG00000022122 Ednrb endothelin receptor type B protein_coding Mus_musculus

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