C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: BRCA1 interacting protein C-terminal helicase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000136492 BRIP1 9606 - 17:61681266-61863521 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000259008 BRIP1-001 61681266-61863521 protein_coding
  ENST00000577598 BRIP1-002 61684772-61861539 protein_coding
  ENST00000577913 BRIP1-003 61857228-61863344 protein_coding
  ENST00000579028 BRIP1-005 61776401-61793673 nonsense_mediated_decay
  ENST00000583837 BRIP1-004 61775878-61780277 processed_transcript
  ENST00000584322 BRIP1-006 61739057-61776480 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000259008ENST00000577598ENST00000579028ENST00000583837
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000259008 0.037±0.00 0.171±0.00 0.092±0.00 0.087±0.00 0.097±0.00 0.682±0.61 0.045±0.00 0.025±0.00 0.118±0.00 0.232±0.00 0.014±0.00 0.956±0.67 0.217±0.05 3.071±1.61
ENST00000577598 N/A N/A N/A 0.067±0.00 N/A 0.040±0.00 N/A N/A 0.056±0.00 0.037±0.00 0.049±0.00 N/A 0.049±0.00 N/A
ENST00000579028 0.315±0.00 0.366±0.00 N/A N/A 0.179±0.00 N/A N/A N/A N/A 0.354±0.00 N/A N/A N/A N/A
ENST00000583837 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.097±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007JV CIL_0007JV_0001 UCNEbase 17:61126460-61946035
CIL_00096P CIL_00096P_0001 VISTA 17:61515758-62116780
CIL_0006ZY CIL_0006ZY_0001 CGP 17:61681266-61928016

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000077 NAS DNA damage checkpoint
GO:0003676 IEA nucleic acid binding
GO:0003677 NAS:IEA DNA binding
GO:0004003 NAS:IEA ATP-dependent DNA helicase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006139 IEA nucleobase-containing compound metabolic process
GO:0006200 IEA ATP catabolic process
GO:0006302 NAS double-strand break repair
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0008026 IEA ATP-dependent helicase activity
GO:0016818 IEA hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
GO:0031965 IDA nuclear membrane
GO:0032508 IEA DNA duplex unwinding
GO:0044281 TAS small molecule metabolic process
GO:0046872 IEA metal ion binding
GO:0051539 IEA 4 iron, 4 sulfur cluster binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074410 brip1 BRCA1 interacting protein C-terminal helicase 1 protein_coding Danio_rerio
ENSMUSG00000034329 Brip1 BRCA1 interacting protein C-terminal helicase 1 protein_coding Mus_musculus

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