C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: GATA binding protein 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000136574 GATA4 9606 + 8:11676959-11760002 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000335135 GATA4-001 11704204-11760002 protein_coding
  ENST00000526021 GATA4-008 11756493-11758765 retained_intron
  ENST00000526716 GATA4-007 11704151-11757082 protein_coding
  ENST00000526974 GATA4-006 11692626-11708381 protein_coding
  ENST00000528027 GATA4-002 11704222-11708662 protein_coding
  ENST00000528712 GATA4-004 11676959-11760000 protein_coding
  ENST00000532059 GATA4-005 11708233-11758522 protein_coding
  ENST00000532977 GATA4-003 11676960-11708360 protein_coding
  ENST00000622443 GATA4-201 11708073-11759131 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000335135ENST00000526021ENST00000526716ENST00000528712ENST00000532059ENST00000622443
Transcript ID Adipose Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000335135 N/A N/A 0.023±0.00 N/A 10.830±8.28 1.759±0.00 8.427±0.00 N/A 33.877±46.84 3.959±0.65 12.882±4.62
ENST00000526021 N/A N/A N/A N/A N/A N/A N/A 0.224±0.00 N/A N/A N/A
ENST00000526716 N/A 0.148±0.00 N/A N/A N/A 0.037±0.00 N/A N/A N/A N/A N/A
ENST00000528712 0.060±0.00 0.061±0.00 N/A N/A N/A N/A 3.118±0.00 0.114±0.00 43.647±0.00 1.118±0.00 N/A
ENST00000532059 N/A N/A 0.077±0.00 0.344±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000622443 N/A N/A N/A N/A N/A 0.620±0.60 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008Y4 CIL_0008Y4_0001 VISTA 8:11271783-11873892
CIL_000919 CIL_000919_0001 VISTA 8:11446673-12047186
CIL_0007PQ CIL_0007PQ_0001 VISTA 8:11649159-12249913

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000790 IEA nuclear chromatin
GO:0000977 IEA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000981 IEA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001076 IDA RNA polymerase II transcription factor binding transcription factor activity
GO:0001158 IEA enhancer sequence-specific DNA binding
GO:0001701 IEA in utero embryonic development
GO:0001702 IEA gastrulation with mouth forming second
GO:0001706 IEA endoderm formation
GO:0001947 ISS heart looping
GO:0003007 IEA heart morphogenesis
GO:0003190 IEA atrioventricular valve formation
GO:0003197 ISS endocardial cushion development
GO:0003208 TAS cardiac ventricle morphogenesis
GO:0003215 ISS cardiac right ventricle morphogenesis
GO:0003229 IEA ventricular cardiac muscle tissue development
GO:0003279 IEA cardiac septum development
GO:0003281 ISS ventricular septum development
GO:0003289 ISS atrial septum primum morphogenesis
GO:0003290 IMP atrial septum secundum morphogenesis
GO:0003677 ISS:IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0003700 IDA:IEA sequence-specific DNA binding transcription factor activity
GO:0003705 IEA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0003713 IDA transcription coactivator activity
GO:0005515 IPI protein binding
GO:0005634 ISS:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0006355 ISS:IEA regulation of transcription, DNA-templated
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0006366 ISS transcription from RNA polymerase II promoter
GO:0007267 ISS cell-cell signaling
GO:0007283 IEA spermatogenesis
GO:0007492 TAS endoderm development
GO:0007507 IEA heart development
GO:0007596 TAS blood coagulation
GO:0008134 IPI transcription factor binding
GO:0008270 IEA zinc ion binding
GO:0008584 IEP male gonad development
GO:0009612 IEA response to mechanical stimulus
GO:0010468 IEA regulation of gene expression
GO:0010507 IEA negative regulation of autophagy
GO:0010575 ISS positive regulation vascular endothelial growth factor production
GO:0014898 IEA cardiac muscle hypertrophy in response to stress
GO:0023019 IEA signal transduction involved in regulation of gene expression
GO:0030509 IEA BMP signaling pathway
GO:0030513 IEA positive regulation of BMP signaling pathway
GO:0032526 IEA response to retinoic acid
GO:0033613 ISS activating transcription factor binding
GO:0035050 IEA embryonic heart tube development
GO:0035054 ISS embryonic heart tube anterior/posterior pattern specification
GO:0035239 IEA tube morphogenesis
GO:0036302 IEA atrioventricular canal development
GO:0042493 IMP response to drug
GO:0043565 ISS:IEA sequence-specific DNA binding
GO:0043627 IEA response to estrogen
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045766 ISS positive regulation of angiogenesis
GO:0045893 ISS:IEA positive regulation of transcription, DNA-templated
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0048557 IEA embryonic digestive tract morphogenesis
GO:0048598 IEA embryonic morphogenesis
GO:0048617 ISS embryonic foregut morphogenesis
GO:0048738 IEA cardiac muscle tissue development
GO:0051525 IEA NFAT protein binding
GO:0051891 ISS positive regulation of cardioblast differentiation
GO:0055007 IEA cardiac muscle cell differentiation
GO:0060008 IEA Sertoli cell differentiation
GO:0060043 IEA regulation of cardiac muscle cell proliferation
GO:0060045 IEA positive regulation of cardiac muscle cell proliferation
GO:0060070 IEA canonical Wnt signaling pathway
GO:0060290 IEA transdifferentiation
GO:0060395 IEA SMAD protein signal transduction
GO:0060413 IMP atrial septum morphogenesis
GO:0060464 IEA lung lobe formation
GO:0060575 IDA intestinal epithelial cell differentiation
GO:0061049 IEA cell growth involved in cardiac muscle cell development
GO:0070410 IPI co-SMAD binding
GO:0071333 IEA cellular response to glucose stimulus
GO:0071371 IEA cellular response to gonadotropin stimulus
GO:0071372 IEA cellular response to follicle-stimulating hormone stimulus
GO:0072148 IEA epithelial cell fate commitment
GO:0072520 IEA seminiferous tubule development
GO:0086004 IEA regulation of cardiac muscle cell contraction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000035759 gata4 GATA-binding protein 4 protein_coding Danio_rerio
ENSMUSG00000021944 Gata4 GATA binding protein 4 protein_coding Mus_musculus

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