C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: thioredoxin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000136810 TXN 9606 - 9:110243811-110256640 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000374515 TXN-002 110243811-110256466 protein_coding
  ENST00000374517 TXN-001 110243811-110256640 protein_coding
  ENST00000487892 TXN-003 110244019-110245116 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000374517
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000374517 56.565±0.00 43.937±0.00 3.126±0.00 31.667±9.36 26.521±20.51 52.868±23.36 10.762±8.23 52.969±35.98 36.524±25.11 53.099±45.07 6.533±2.90 83.405±41.62 65.536±21.74 21.222±16.14

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007PS CIL_0007PS_0001 VISTA 9:109825819-110428061
CIL_0007HP CIL_0007HP_0001 CGP 9:110190048-110256640
CIL_00016I CIL_00016I_0001 CGP 9:110243811-110337884

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005681 IEA spliceosomal complex
GO:0005737 IDA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005829 TAS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006662 IEA glycerol ether metabolic process
GO:0006928 TAS cellular component movement
GO:0007067 IEA mitotic nuclear division
GO:0007165 TAS signal transduction
GO:0007267 TAS cell-cell signaling
GO:0008283 TAS cell proliferation
GO:0009314 IDA response to radiation
GO:0015035 IEA protein disulfide oxidoreductase activity
GO:0015037 IEA peptide disulfide oxidoreductase activity
GO:0015949 TAS nucleobase-containing small molecule interconversion
GO:0032148 IC activation of protein kinase B activity
GO:0033138 IGI positive regulation of peptidyl-serine phosphorylation
GO:0033158 IDA regulation of protein import into nucleus, translocation
GO:0035872 TAS nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway
GO:0043388 IDA positive regulation of DNA binding
GO:0044281 TAS small molecule metabolic process
GO:0044822 IDA poly(A) RNA binding
GO:0045087 TAS innate immune response
GO:0045454 IEA cell redox homeostasis
GO:0046826 IEA negative regulation of protein export from nucleus
GO:0051897 IC positive regulation of protein kinase B signaling
GO:0055086 TAS nucleobase-containing small molecule metabolic process
GO:0055114 IDA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome
GO:1903206 IGI negative regulation of hydrogen peroxide-induced cell death

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000031435 zgc:56493 zgc:56493 protein_coding Danio_rerio
ENSDARG00000044125 txn thioredoxin protein_coding Danio_rerio
ENSMUSG00000028367 Txn1 thioredoxin 1 protein_coding Mus_musculus

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