C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: v-myc avian myelocytomatosis viral oncogene homolog
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000136997 MYC 9606 + 8:127735434-127741434 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000259523 MYC-002 127735434-127740477 protein_coding
  ENST00000377970 MYC-006 127736084-127741434 protein_coding
  ENST00000517291 MYC-003 127735519-127738772 protein_coding
  ENST00000520751 MYC-005 127736231-127738475 protein_coding
  ENST00000524013 MYC-004 127736220-127741372 protein_coding
  ENST00000613283 MYC-201 127736069-127741432 protein_coding
  ENST00000621592 MYC-001 127736084-127741434 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000377970ENST00000524013ENST00000613283
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000377970 N/A N/A N/A 0.418±0.00 N/A 2.496±0.00 N/A 1.970±0.00 N/A 1.451±0.00 N/A 18.117±0.00 8.812±4.59 N/A
ENST00000524013 37.509±0.00 16.060±0.00 1.386±0.00 2.392±0.00 18.695±11.27 13.929±8.46 3.330±2.47 3.203±2.94 5.549±3.66 21.879±0.00 30.369±25.30 39.998±27.72 6.220±1.10 6.844±3.73
ENST00000613283 12.717±0.00 N/A N/A N/A 5.169±0.22 5.134±0.00 1.108±0.00 1.607±0.00 4.574±0.00 4.226±0.00 9.142±0.00 15.438±3.16 4.110±0.00 2.016±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000165 IMP MAPK cascade
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001658 ISS branching involved in ureteric bud morphogenesis
GO:0002053 ISS positive regulation of mesenchymal cell proliferation
GO:0003677 ISS DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA:IEA nucleus
GO:0005654 IDA nucleoplasm
GO:0005730 IDA nucleolus
GO:0005819 IEA spindle
GO:0006112 NAS energy reserve metabolic process
GO:0006338 IDA chromatin remodeling
GO:0006351 TAS transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0006879 IDA cellular iron ion homeostasis
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0007050 IDA cell cycle arrest
GO:0007179 TAS transforming growth factor beta receptor signaling pathway
GO:0007219 TAS Notch signaling pathway
GO:0008134 IPI transcription factor binding
GO:0008284 IDA positive regulation of cell proliferation
GO:0010332 IDA response to gamma radiation
GO:0010467 TAS gene expression
GO:0010468 IDA regulation of gene expression
GO:0015671 NAS oxygen transport
GO:0032204 IMP regulation of telomere maintenance
GO:0032403 IDA protein complex binding
GO:0032873 ISS negative regulation of stress-activated MAPK cascade
GO:0034644 IEP cellular response to UV
GO:0035690 IDA cellular response to drug
GO:0042493 IEP response to drug
GO:0043066 ISS negative regulation of apoptotic process
GO:0043234 IDA protein complex
GO:0043280 IDA positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0044346 TAS fibroblast apoptotic process
GO:0045656 IMP negative regulation of monocyte differentiation
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046983 IEA protein dimerization activity
GO:0048146 IMP positive regulation of fibroblast proliferation
GO:0048147 IDA negative regulation of fibroblast proliferation
GO:0050679 IDA positive regulation of epithelial cell proliferation
GO:0051276 IDA chromosome organization
GO:0051782 IDA negative regulation of cell division
GO:0060070 IDA canonical Wnt signaling pathway
GO:0070491 IPI repressing transcription factor binding
GO:0070848 TAS response to growth factor
GO:0070888 IDA E-box binding
GO:0090096 ISS positive regulation of metanephric cap mesenchymal cell proliferation
GO:2000573 IMP positive regulation of DNA biosynthetic process
GO:2001022 IDA positive regulation of response to DNA damage stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007241 mycb myelocytomatosis oncogene b protein_coding Danio_rerio
ENSDARG00000045695 myca myelocytomatosis oncogene a protein_coding Danio_rerio
ENSMUSG00000049086 Bmyc brain expressed myelocytomatosis oncogene protein_coding Mus_musculus

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