C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glyoxylate reductase/hydroxypyruvate reductase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000137106 GRHPR 9606 + 9:37422666-37436990 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000318158 GRHPR-002 37422666-37436990 protein_coding
  ENST00000377824 GRHPR-004 37422714-37431719 retained_intron
  ENST00000460882 GRHPR-001 37422696-37436848 processed_transcript
  ENST00000480596 GRHPR-005 37428538-37436987 retained_intron
  ENST00000482603 GRHPR-009 37429786-37432811 processed_transcript
  ENST00000487399 GRHPR-010 37422714-37426650 processed_transcript
  ENST00000491488 GRHPR-008 37422725-37436692 processed_transcript
  ENST00000493368 GRHPR-003 37422666-37429158 processed_transcript
  ENST00000494290 GRHPR-006 37428995-37436990 nonsense_mediated_decay
  ENST00000497693 GRHPR-007 37427706-37436989 retained_intron
  ENST00000512404 GRHPR-012 37432087-37433881 processed_transcript
  ENST00000607784 GRHPR-011 37422746-37434879 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000318158ENST00000377824ENST00000460882ENST00000491488ENST00000493368ENST00000497693
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000318158 25.605±0.00 29.811±0.00 13.941±0.00 19.898±6.81 19.347±10.24 10.252±2.93 20.294±8.95 67.287±26.18 76.236±65.75 14.481±10.96 20.819±13.96 45.207±33.35 43.585±10.94 19.303±8.12
ENST00000377824 N/A N/A N/A N/A N/A 1.160±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000460882 22.944±0.00 23.382±0.00 6.558±0.00 17.882±14.58 31.123±0.00 12.601±10.58 15.520±0.00 36.231±3.73 70.154±0.00 10.831±7.57 14.146±6.04 20.806±10.28 10.471±1.02 18.381±11.16
ENST00000491488 N/A N/A N/A 35.349±0.00 18.605±0.00 15.704±0.00 N/A N/A N/A N/A N/A 29.711±0.00 26.618±0.00 19.733±1.44
ENST00000493368 N/A N/A N/A 2.799±0.00 N/A 2.253±0.00 N/A N/A N/A N/A N/A 2.351±0.00 N/A N/A
ENST00000497693 N/A N/A N/A N/A 0.728±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000843 CIL_000843_0001 VISTA 9:36915019-37515778
CIL_0008YP CIL_0008YP_0001 VISTA 9:36951210-37552226
CIL_00080S CIL_00080S_0001 VISTA 9:37036633-37638309
CIL_00035L CIL_00035L_0001 CGP 9:37120539-37436990
CIL_0006K9 CIL_0006K9_0001 CGP 9:37422666-37465399

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004616 IEA phosphogluconate dehydrogenase (decarboxylating) activity
GO:0005737 IDA cytoplasm
GO:0005782 TAS peroxisomal matrix
GO:0005829 IEA cytosol
GO:0006098 IEA pentose-phosphate shunt
GO:0007588 IMP excretion
GO:0008152 NAS:IEA metabolic process
GO:0008465 IDA glycerate dehydrogenase activity
GO:0016616 IEA oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0016618 IDA hydroxypyruvate reductase activity
GO:0030267 IDA glyoxylate reductase (NADP) activity
GO:0031406 IEA carboxylic acid binding
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0042803 IDA protein homodimerization activity
GO:0043648 IEA dicarboxylic acid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0046487 TAS glyoxylate metabolic process
GO:0050661 IEA NADP binding
GO:0051259 IDA protein oligomerization
GO:0051287 TAS:IEA NAD binding
GO:0055114 IDA:IEA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome
GO:0070402 IDA NADPH binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000068264 grhpra glyoxylate reductase/hydroxypyruvate reductase a protein_coding Danio_rerio
ENSMUSG00000035637 Grhpr glyoxylate reductase/hydroxypyruvate reductase protein_coding Mus_musculus

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