C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: thiopurine S-methyltransferase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000137364 TPMT 9606 - 6:18128311-18155074 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000309983 TPMT-001 18128311-18155074 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000309983
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000309983 2.576±0.00 3.675±0.00 3.909±0.00 4.278±2.32 1.415±0.06 4.443±0.23 2.645±1.84 8.765±4.95 8.376±6.00 2.299±0.55 1.355±0.22 4.202±3.10 3.109±0.78 4.719±0.91

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00090E CIL_00090E_0001 VISTA 6:17631749-18233261
CIL_0003RL CIL_0003RL_0001 CGP 6:18121419-18155074
CIL_0003RU CIL_0003RU_0001 CGP 6:18128311-18223853

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005829 TAS cytosol
GO:0006139 TAS nucleobase-containing compound metabolic process
GO:0006805 TAS xenobiotic metabolic process
GO:0008119 IEA thiopurine S-methyltransferase activity
GO:0008757 IEA S-adenosylmethionine-dependent methyltransferase activity
GO:0032259 TAS methylation
GO:0044281 TAS small molecule metabolic process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000028012 TPMT (1 of 2) thiopurine S-methyltransferase protein_coding Danio_rerio
ENSDARG00000055974 TPMT (2 of 2) thiopurine S-methyltransferase protein_coding Danio_rerio
ENSMUSG00000021376 Tpmt thiopurine methyltransferase protein_coding Mus_musculus

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