C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phospholipase C, beta 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000137841 PLCB2 9606 - 15:40278176-40307935 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000260402 PLCB2-001 40287907-40307922 protein_coding
  ENST00000456256 PLCB2-003 40288139-40307825 protein_coding
  ENST00000543785 PLCB2-002 40300667-40307910 protein_coding
  ENST00000557821 PLCB2-004 40287909-40307837 protein_coding
  ENST00000558409 PLCB2-010 40296565-40297719 retained_intron
  ENST00000558505 PLCB2-015 40288572-40291330 retained_intron
  ENST00000558588 PLCB2-006 40287909-40307693 retained_intron
  ENST00000559381 PLCB2-007 40287908-40291329 retained_intron
  ENST00000559618 PLCB2-016 40287909-40289292 nonsense_mediated_decay
  ENST00000559634 PLCB2-008 40303887-40307935 retained_intron
  ENST00000559671 PLCB2-013 40284256-40290672 protein_coding
  ENST00000560009 PLCB2-014 40278176-40289572 retained_intron
  ENST00000560093 PLCB2-009 40298294-40299289 retained_intron
  ENST00000560701 PLCB2-012 40289066-40291353 retained_intron
  ENST00000561378 PLCB2-011 40291874-40293622 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000260402ENST00000456256ENST00000543785ENST00000557821ENST00000558409ENST00000558505ENST00000558588ENST00000559381ENST00000559618ENST00000559634ENST00000559671ENST00000560093ENST00000561378
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000260402 N/A N/A N/A 0.155±0.00 N/A N/A N/A N/A 0.491±0.00 N/A N/A N/A N/A N/A
ENST00000456256 0.668±0.00 3.720±0.00 N/A 0.703±0.00 1.020±0.35 N/A 0.310±0.26 0.704±0.00 N/A N/A 0.042±0.01 0.637±0.30 1.885±0.24 0.571±0.00
ENST00000543785 N/A N/A N/A N/A N/A N/A 0.250±0.00 0.704±0.00 N/A N/A N/A N/A N/A N/A
ENST00000557821 N/A N/A N/A N/A N/A N/A N/A N/A 0.370±0.00 0.845±0.54 N/A 0.450±0.10 1.419±0.07 N/A
ENST00000558409 N/A N/A N/A N/A N/A 0.414±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000558505 N/A N/A N/A 1.087±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000558588 N/A 2.008±0.00 N/A 0.235±0.00 N/A 0.363±0.00 N/A 0.129±0.00 N/A 0.992±0.00 N/A 0.598±0.06 1.073±0.00 0.518±0.03
ENST00000559381 0.752±0.00 8.803±0.00 N/A 0.885±0.56 1.893±0.00 N/A 1.304±0.00 N/A N/A 2.804±0.00 0.145±0.00 2.851±1.94 3.209±0.87 2.586±2.10
ENST00000559618 N/A N/A N/A N/A N/A 0.338±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000559634 N/A N/A N/A N/A N/A N/A 0.749±0.00 N/A N/A N/A N/A 0.959±0.00 N/A N/A
ENST00000559671 N/A N/A 0.188±0.00 N/A N/A N/A N/A 1.211±0.00 N/A N/A N/A N/A N/A N/A
ENST00000560093 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.232±0.00 N/A N/A N/A
ENST00000561378 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.314±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008W0 CIL_0008W0_0001 VISTA 15:39791359-40393937

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004435 IEA phosphatidylinositol phospholipase C activity
GO:0004629 TAS phospholipase C activity
GO:0004871 IEA signal transducer activity
GO:0005509 IEA calcium ion binding
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005829 TAS cytosol
GO:0006629 IEA lipid metabolic process
GO:0006644 TAS phospholipid metabolic process
GO:0007165 IEA signal transduction
GO:0007202 TAS activation of phospholipase C activity
GO:0007268 TAS synaptic transmission
GO:0008081 IEA phosphoric diester hydrolase activity
GO:0008152 IEA metabolic process
GO:0016042 IEA lipid catabolic process
GO:0035556 IEA intracellular signal transduction
GO:0043647 TAS inositol phosphate metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0050913 IEA sensory perception of bitter taste

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000090381 PLCB2 phospholipase C, beta 2 protein_coding Danio_rerio
ENSMUSG00000040061 Plcb2 phospholipase C, beta 2 protein_coding Mus_musculus

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