C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: retinol binding protein 4, plasma
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000138207 RBP4 9606 - 10:93591687-93601744 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000371464 RBP4-001 93591687-93601226 protein_coding
  ENST00000371467 RBP4-003 93591687-93601663 protein_coding
  ENST00000371469 RBP4-002 93591889-93601744 protein_coding
  ENST00000615669 RBP4-201 93591844-93601203 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000371464ENST00000371467ENST00000371469ENST00000615669
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000371464 66.174±0.00 0.583±0.00 4.830±0.00 2.996±1.53 99.574±93.08 0.529±0.00 1.198±0.00 216.826±213.60 8.186±0.00 1.919±0.00 0.286±0.00 4.970±5.10 10.748±2.86 1.066±0.75
ENST00000371467 N/A N/A N/A N/A 1.187±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000371469 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.144±0.00 17.272±2.12 N/A
ENST00000615669 120.835±0.00 1.658±0.00 5.838±0.00 7.431±3.34 190.239±186.77 4.308±1.25 1.139±0.56 742.145±710.01 1822.071±1820.31 32.911±0.00 1.201±0.00 13.111±16.68 13.064±9.68 3.850±1.53

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00068O CIL_00068O_0001 CGP 10:93496632-93604480
CIL_000101 CIL_000101_0001 CGP 10:93566665-93604480
CIL_000102 CIL_000102_0001 CGP 10:93591687-93666010

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001523 TAS retinoid metabolic process
GO:0001654 ISS eye development
GO:0005215 IEA transporter activity
GO:0005501 IEA retinoid binding
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005615 ISS extracellular space
GO:0005829 TAS cytosol
GO:0006094 ISS gluconeogenesis
GO:0006810 IEA transport
GO:0007283 IEA spermatogenesis
GO:0007507 ISS heart development
GO:0007603 TAS phototransduction, visible light
GO:0008584 IEA male gonad development
GO:0016918 IEA retinal binding
GO:0019841 IDA retinol binding
GO:0030277 IDA maintenance of gastrointestinal epithelium
GO:0030324 ISS lung development
GO:0032024 IMP positive regulation of insulin secretion
GO:0032526 IDA response to retinoic acid
GO:0032868 IEA response to insulin
GO:0034632 IC retinol transporter activity
GO:0034633 IC retinol transport
GO:0036094 IEA small molecule binding
GO:0042572 IMP retinol metabolic process
GO:0042574 IEA retinal metabolic process
GO:0042593 IDA glucose homeostasis
GO:0043234 IEA protein complex
GO:0045471 IEA response to ethanol
GO:0046982 IEA protein heterodimerization activity
GO:0048562 ISS embryonic organ morphogenesis
GO:0048706 ISS embryonic skeletal system development
GO:0048738 ISS cardiac muscle tissue development
GO:0048807 ISS female genitalia morphogenesis
GO:0050908 IEA detection of light stimulus involved in visual perception
GO:0051024 ISS positive regulation of immunoglobulin secretion
GO:0060041 IEA retina development in camera-type eye
GO:0060044 ISS negative regulation of cardiac muscle cell proliferation
GO:0060059 ISS embryonic retina morphogenesis in camera-type eye
GO:0060065 ISS uterus development
GO:0060068 ISS vagina development
GO:0060157 ISS urinary bladder development
GO:0060347 ISS heart trabecula formation
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077505 rbp4 retinol binding protein 4, plasma protein_coding Danio_rerio
ENSMUSG00000024990 Rbp4 retinol binding protein 4, plasma protein_coding Mus_musculus

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