C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: corepressor interacting with RBPJ, 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000138433 CIR1 9606 - 2:174348022-174395715 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000342016 CIR1-001 174348022-174395715 protein_coding
  ENST00000377973 CIR1-007 174358173-174380680 protein_coding
  ENST00000461454 CIR1-005 174378687-174395706 retained_intron
  ENST00000464393 CIR1-006 174349135-174351963 retained_intron
  ENST00000472169 CIR1-004 174387263-174395709 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000342016ENST00000461454ENST00000464393
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000342016 8.042±0.00 0.394±0.00 7.415±5.92 4.199±3.16 5.954±5.42 3.459±3.19 6.991±0.00 1.993±0.38 4.413±3.52 2.710±2.59 7.489±4.07 10.518±1.75 18.741±0.80
ENST00000461454 N/A 1.958±0.00 0.893±0.00 2.016±0.00 1.452±0.00 0.990±0.00 N/A 1.874±0.00 4.502±0.00 0.572±0.00 2.286±0.00 N/A N/A
ENST00000464393 N/A N/A N/A 3.622±0.00 N/A N/A N/A N/A 4.515±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007OE CIL_0007OE_0001 UCNEbase 2:173198009-174351945
CIL_0008JW CIL_0008JW_0001 VISTA 2:173820816-174422736
CIL_0008K1 CIL_0008K1_0001 VISTA 2:173824009-174425635
CIL_0008S8 CIL_0008S8_0001 VISTA 2:173876675-174477772
CIL_00096H CIL_00096H_0001 VISTA 2:174031315-174632386
CIL_0008GI CIL_0008GI_0001 VISTA 2:174038535-174640167
CIL_0008K2 CIL_0008K2_0001 VISTA 2:174042582-174643514
CIL_0001HA CIL_0001HA_0001 CGP 2:174334946-174395715
CIL_0003IH CIL_0003IH_0002 CGP 2:174348022-174429575

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000118 IDA histone deacetylase complex
GO:0003676 IEA nucleic acid binding
GO:0003700 TAS sequence-specific DNA binding transcription factor activity
GO:0003705 TAS RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0003714 TAS transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0006357 TAS regulation of transcription from RNA polymerase II promoter
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0006397 IEA mRNA processing
GO:0008270 IEA zinc ion binding
GO:0008380 IEA RNA splicing
GO:0045892 IDA negative regulation of transcription, DNA-templated

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044418 CIR1 corepressor interacting with RBPJ, 1 protein_coding Danio_rerio
ENSMUSG00000041777 Cir1 corepressor interacting with RBPJ, 1 protein_coding Mus_musculus

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