C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: abl-interactor 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000138443 ABI2 9606 + 2:203328219-203447723 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000261016 ABI2-201 203328239-203432172 protein_coding
  ENST00000261017 ABI2-002 203328280-203432173 protein_coding
  ENST00000261018 ABI2-202 203328239-203432172 protein_coding
  ENST00000295851 ABI2-001 203328219-203447723 protein_coding
  ENST00000376135 ABI2-015 203328459-203383296 processed_transcript
  ENST00000411547 ABI2-016 203380226-203402677 processed_transcript
  ENST00000413635 ABI2-011 203328395-203376132 nonsense_mediated_decay
  ENST00000416001 ABI2-003 203328391-203427569 nonsense_mediated_decay
  ENST00000416396 ABI2-021 203394748-203427219 processed_transcript
  ENST00000417864 ABI2-006 203328407-203427269 protein_coding
  ENST00000422511 ABI2-007 203328484-203428596 protein_coding
  ENST00000422719 ABI2-017 203380358-203416972 processed_transcript
  ENST00000424558 ABI2-005 203328395-203427948 protein_coding
  ENST00000425253 ABI2-023 203328394-203366957 nonsense_mediated_decay
  ENST00000430418 ABI2-004 203328392-203427528 protein_coding
  ENST00000430574 ABI2-019 203380275-203416983 processed_transcript
  ENST00000431886 ABI2-013 203328399-203380277 nonsense_mediated_decay
  ENST00000441061 ABI2-008 203328336-203427528 nonsense_mediated_decay
  ENST00000444584 ABI2-014 203328405-203380273 nonsense_mediated_decay
  ENST00000447762 ABI2-024 203328282-203380306 nonsense_mediated_decay
  ENST00000451591 ABI2-018 203380308-203402734 protein_coding
  ENST00000454023 ABI2-020 203391044-203427411 protein_coding
  ENST00000464761 ABI2-022 203402706-203436883 processed_transcript
  ENST00000494215 ABI2-012 203328458-203367419 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000261016ENST00000261017ENST00000261018ENST00000416001
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000261016 N/A N/A 1.534±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000261017 4.804±0.00 4.399±0.00 2.543±0.00 6.425±1.38 4.414±0.30 5.052±2.59 3.297±1.46 8.190±0.00 6.170±0.00 6.081±0.68 1.107±0.26 7.421±3.65 4.086±0.21 8.980±1.79
ENST00000261018 N/A N/A N/A 15.040±2.57 N/A N/A 3.496±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000416001 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 23.616±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000JP CIL_0000JP_0002 CGP 2:203238449-203447723
CIL_0000JQ CIL_0000JQ_0002 CGP 2:203328219-203535410

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003677 TAS DNA binding
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005829 IDA cytosol
GO:0005856 IEA cytoskeleton
GO:0005913 IEA cell-cell adherens junction
GO:0006928 IDA cellular component movement
GO:0007010 TAS cytoskeleton organization
GO:0007611 IEA learning or memory
GO:0008093 TAS cytoskeletal adaptor activity
GO:0008154 NAS actin polymerization or depolymerization
GO:0016358 IEA dendrite development
GO:0016477 TAS cell migration
GO:0016601 IDA Rac protein signal transduction
GO:0017124 IPI SH3 domain binding
GO:0018108 IDA peptidyl-tyrosine phosphorylation
GO:0019900 NAS kinase binding
GO:0030027 IDA lamellipodium
GO:0030175 IDA filopodium
GO:0030425 IEA dendrite
GO:0031209 IDA SCAR complex
GO:0031625 IPI ubiquitin protein ligase binding
GO:0032403 IDA protein complex binding
GO:0043010 IEA camera-type eye development
GO:0048365 IDA Rac GTPase binding
GO:0070064 IPI proline-rich region binding
GO:2000601 IDA positive regulation of Arp2/3 complex-mediated actin nucleation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014875 abi2b abl-interactor 2b protein_coding Danio_rerio
ENSDARG00000058207 abi2a abl-interactor 2a protein_coding Danio_rerio
ENSMUSG00000026782 Abi2 abl-interactor 2 protein_coding Mus_musculus

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