C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: solute carrier family 40 (iron-regulated transporter), member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000138449 SLC40A1 9606 - 2:189560579-189583758 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000261024 SLC40A1-001 189560579-189580887 protein_coding
  ENST00000418714 SLC40A1-008 189575161-189580783 processed_transcript
  ENST00000427241 SLC40A1-002 189565513-189583758 protein_coding
  ENST00000427419 SLC40A1-003 189579848-189582022 protein_coding
  ENST00000440626 SLC40A1-005 189579848-189583402 protein_coding
  ENST00000455320 SLC40A1-004 189575266-189582031 protein_coding
  ENST00000479598 SLC40A1-006 189572521-189580741 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000261024
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000261024 13.033±0.00 26.222±0.00 6.458±0.00 1.029±0.00 18.108±3.40 16.413±3.82 6.133±2.44 17.691±4.66 27.226±0.00 23.212±13.41 10.875±4.12 53.609±30.61 79.676±37.93 21.081±5.97

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002260 IEA lymphocyte homeostasis
GO:0003158 IEA endothelium development
GO:0005381 IMP:IEA iron ion transmembrane transporter activity
GO:0005515 IPI protein binding
GO:0005622 IDA intracellular
GO:0005737 TAS cytoplasm
GO:0005771 IEA multivesicular body
GO:0005886 IDA plasma membrane
GO:0005887 IC integral component of plasma membrane
GO:0006826 IEA iron ion transport
GO:0006879 IMP cellular iron ion homeostasis
GO:0008021 IEA synaptic vesicle
GO:0009653 TAS anatomical structure morphogenesis
GO:0016021 IEA:TAS integral component of membrane
GO:0016323 IDA basolateral plasma membrane
GO:0034395 IEA regulation of transcription from RNA polymerase II promoter in response to iron
GO:0034755 IEA:IMP iron ion transmembrane transport
GO:0043066 IEA negative regulation of apoptotic process
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0048536 IEA spleen development
GO:0055085 TAS transmembrane transport
GO:0060345 IEA spleen trabecula formation
GO:0060586 IEA multicellular organismal iron ion homeostasis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000000241 slc40a1 solute carrier family 40 (iron-regulated transporter), member 1 protein_coding Danio_rerio
ENSMUSG00000025993 Slc40a1 solute carrier family 40 (iron-regulated transporter), member 1 protein_coding Mus_musculus

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