C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000138623 SEMA7A 9606 - 15:74409289-74434467 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000261918 SEMA7A-001 74409289-74434467 protein_coding
  ENST00000542748 SEMA7A-201 74409290-74433660 protein_coding
  ENST00000543145 SEMA7A-002 74410316-74433955 protein_coding
  ENST00000567345 SEMA7A-005 74416639-74433704 protein_coding
  ENST00000569617 SEMA7A-004 74410968-74411639 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000261918ENST00000542748ENST00000543145ENST00000567345
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000261918 N/A N/A N/A N/A N/A N/A N/A N/A 0.059±0.00 N/A 0.073±0.00 N/A N/A N/A
ENST00000542748 0.932±0.00 14.121±0.00 N/A 13.112±12.17 0.889±0.00 0.733±0.00 0.357±0.00 0.443±0.00 0.245±0.19 16.326±0.00 0.069±0.00 6.225±6.12 47.735±12.77 24.172±1.25
ENST00000543145 N/A N/A 0.138±0.00 7.648±5.72 0.061±0.00 0.276±0.00 0.053±0.02 0.221±0.00 0.424±0.00 2.533±2.25 0.252±0.00 1.825±0.48 12.671±0.00 N/A
ENST00000567345 N/A N/A 0.098±0.00 N/A N/A N/A N/A N/A 0.129±0.00 N/A N/A 2.057±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007UD CIL_0007UD_0001 VISTA 15:74278506-74880453

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001649 IDA osteoblast differentiation
GO:0001934 IEA positive regulation of protein phosphorylation
GO:0004872 IEA receptor activity
GO:0005178 IEA integrin binding
GO:0005515 IPI:IEA protein binding
GO:0005886 TAS plasma membrane
GO:0006954 IEA inflammatory response
GO:0006955 TAS immune response
GO:0007229 IDA integrin-mediated signaling pathway
GO:0007275 IEA multicellular organismal development
GO:0007411 TAS axon guidance
GO:0009897 ISS external side of plasma membrane
GO:0016020 IDA:IEA membrane
GO:0021988 IEA olfactory lobe development
GO:0031175 IEA neuron projection development
GO:0031225 IEA anchored component of membrane
GO:0045773 IDA positive regulation of axon extension
GO:0048675 IEA axon extension
GO:0050727 ISS regulation of inflammatory response
GO:0060907 ISS positive regulation of macrophage cytokine production
GO:0070374 IDA positive regulation of ERK1 and ERK2 cascade

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000078707 sema7a semaphorin 7A protein_coding Danio_rerio
ENSDARG00000090776 SEMA7A (2 of 2) semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) protein_coding Danio_rerio
ENSMUSG00000038264 Sema7a sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A protein_coding Mus_musculus

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