C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: pyrophosphatase (inorganic) 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000138777 PPA2 9606 - 4:105369077-105474081 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000341695 PPA2-001 105369077-105474081 protein_coding
  ENST00000348706 PPA2-002 105369243-105474064 protein_coding
  ENST00000351450 PPA2-004 105369565-105474067 nonsense_mediated_decay
  ENST00000354147 PPA2-006 105369565-105474050 protein_coding
  ENST00000432483 PPA2-007 105369565-105474050 protein_coding
  ENST00000457404 PPA2-011 105405838-105474062 processed_transcript
  ENST00000499847 PPA2-013 105446202-105474059 retained_intron
  ENST00000502596 PPA2-021 105437977-105473709 protein_coding
  ENST00000502610 PPA2-018 105456081-105474032 retained_intron
  ENST00000502833 PPA2-016 105423204-105474059 processed_transcript
  ENST00000503171 PPA2-020 105386613-105453908 processed_transcript
  ENST00000504028 PPA2-015 105424249-105474059 protein_coding
  ENST00000505713 PPA2-012 105473358-105474059 processed_transcript
  ENST00000506815 PPA2-010 105405637-105473987 nonsense_mediated_decay
  ENST00000508518 PPA2-017 105399079-105474040 protein_coding
  ENST00000509031 PPA2-008 105369561-105474014 nonsense_mediated_decay
  ENST00000509426 PPA2-005 105398304-105474059 processed_transcript
  ENST00000510015 PPA2-022 105396326-105474059 protein_coding
  ENST00000513605 PPA2-009 105369565-105399636 retained_intron
  ENST00000513649 PPA2-014 105438015-105474059 nonsense_mediated_decay
  ENST00000514209 PPA2-019 105399151-105474059 nonsense_mediated_decay
  ENST00000515567 PPA2-003 105369565-105449371 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000341695ENST00000348706ENST00000351450ENST00000354147ENST00000457404ENST00000499847ENST00000502596ENST00000502833ENST00000509031ENST00000510015
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000341695 N/A N/A N/A 3.952±0.00 N/A N/A N/A N/A 3.422±0.00 N/A N/A 7.503±0.00 1.454±0.00 N/A
ENST00000348706 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.806±0.00 2.153±0.00 2.130±0.00 N/A
ENST00000351450 9.341±0.00 12.852±0.00 N/A 9.920±0.02 10.583±5.31 12.294±0.00 11.467±7.19 21.647±9.60 14.536±0.00 7.371±0.48 3.727±1.51 12.884±7.37 7.759±3.66 14.558±0.00
ENST00000354147 11.799±0.00 12.395±0.00 N/A 13.958±0.00 12.873±0.00 7.544±0.00 16.114±0.00 19.672±0.00 9.187±0.00 13.150±0.00 1.364±0.00 8.119±0.00 6.167±0.00 11.137±0.00
ENST00000457404 N/A N/A N/A N/A N/A N/A 6.667±0.00 N/A N/A 9.881±0.00 N/A 10.908±0.00 8.443±3.28 12.473±0.00
ENST00000499847 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 11.886±0.00 14.969±0.00 12.368±0.00
ENST00000502596 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.405±0.00 N/A N/A N/A
ENST00000502833 N/A N/A N/A N/A 7.592±0.00 N/A N/A N/A 9.856±0.00 N/A N/A 9.559±0.00 N/A N/A
ENST00000509031 N/A N/A N/A 6.454±0.00 3.813±0.00 N/A N/A N/A 4.684±0.00 3.645±0.00 N/A N/A N/A N/A
ENST00000510015 N/A N/A 116.869±0.00 41.191±0.00 38.591±0.00 157.042±0.00 28.885±0.00 58.324±0.00 50.768±0.00 35.768±0.00 39.177±0.00 66.920±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006P2 CIL_0006P2_0002 CGP 4:105145875-105474081
CIL_0006P5 CIL_0006P5_0002 CGP 4:105369077-105708093

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 IEA magnesium ion binding
GO:0004427 IEA:TAS inorganic diphosphatase activity
GO:0004722 IEA protein serine/threonine phosphatase activity
GO:0005737 IEA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005759 TAS mitochondrial matrix
GO:0006418 TAS tRNA aminoacylation for protein translation
GO:0006796 IEA phosphate-containing compound metabolic process
GO:0010467 TAS gene expression
GO:0016311 IEA dephosphorylation
GO:0070062 IDA extracellular vesicular exosome
GO:0071344 TAS diphosphate metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000009685 ppa2 pyrophosphatase (inorganic) 2 protein_coding Danio_rerio
ENSMUSG00000028013 Ppa2 pyrophosphatase (inorganic) 2 protein_coding Mus_musculus

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