C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphodiesterase 6H, cGMP-specific, cone, gamma
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000139053 PDE6H 9606 + 12:14973022-14981865 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000266395 PDE6H-001 14973022-14981865 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastPlacentaTestisENST00000266395
Transcript ID Brain Breast Placenta Testis
ENST00000266395 0.505±0.00 0.081±0.00 0.559±0.42 0.046±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000373 CIL_000373_0001 CGP 12:14942017-14981865
CIL_000374 CIL_000374_0001 CGP 12:14973022-15348675

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000187 IEA activation of MAPK activity
GO:0004114 IEA 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0004857 TAS enzyme inhibitor activity
GO:0007601 IEA visual perception
GO:0008152 IEA metabolic process
GO:0030553 IEA cGMP binding
GO:0043086 TAS negative regulation of catalytic activity
GO:0045742 IEA positive regulation of epidermal growth factor receptor signaling pathway
GO:0045745 IEA positive regulation of G-protein coupled receptor protein signaling pathway
GO:0047555 IEA 3',5'-cyclic-GMP phosphodiesterase activity
GO:0050896 IEA response to stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000056791 PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma protein_coding Danio_rerio
ENSMUSG00000064330 Pde6h phosphodiesterase 6H, cGMP-specific, cone, gamma protein_coding Mus_musculus

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