C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: fibroblast growth factor 7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000140285 FGF7 9606 + 15:49423096-49488775 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000267843 FGF7-001 49423096-49488775 protein_coding
  ENST00000560270 FGF7-002 49423237-49425515 protein_coding
  ENST00000560704 FGF7-003 49434396-49484520 processed_transcript
  ENST00000560765 FGF7-005 49423258-49484559 nonsense_mediated_decay
  ENST00000560979 FGF7-004 49423260-49484460 protein_coding
  ENST00000614567 FGF7-201 49423178-49487326 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000267843ENST00000560270ENST00000560704ENST00000560765ENST00000560979ENST00000614567
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000267843 5.001±0.00 4.382±0.00 0.428±0.00 0.365±0.00 2.172±0.97 3.931±3.22 1.455±0.82 0.952±0.00 0.972±0.94 7.345±6.32 0.870±0.00 1.636±1.13 0.450±0.02 1.206±0.49
ENST00000560270 N/A N/A N/A N/A N/A 1.135±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000560704 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.388±0.00 N/A N/A N/A
ENST00000560765 11.968±0.00 8.814±0.00 0.813±0.00 N/A 9.496±7.23 13.116±8.62 3.271±0.54 N/A 14.751±0.00 34.726±24.13 N/A 8.636±5.65 1.150±0.59 4.077±0.00
ENST00000560979 N/A N/A 1.044±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 1.545±0.00 5.055±0.00 N/A
ENST00000614567 N/A N/A N/A 0.140±0.00 N/A 0.852±0.00 0.842±0.00 0.209±0.00 1.228±1.18 0.824±0.00 N/A 0.852±0.00 0.290±0.18 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002E2 CIL_0002E2_0001 CGP 15:49155656-49620931
CIL_0002E5 CIL_0002E5_0001 CGP 15:49326962-49620931
CIL_000505 CIL_000505_0002 CGP 15:49423096-49656232

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005104 IEA fibroblast growth factor receptor binding
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005794 IEA Golgi apparatus
GO:0007165 NAS signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0008083 IEA growth factor activity
GO:0008201 IEA heparin binding
GO:0008284 IGI positive regulation of cell proliferation
GO:0008286 TAS insulin receptor signaling pathway
GO:0008543 IEA:IGI fibroblast growth factor receptor signaling pathway
GO:0008544 TAS epidermis development
GO:0009611 TAS response to wounding
GO:0010463 IDA mesenchymal cell proliferation
GO:0010838 IDA positive regulation of keratinocyte proliferation
GO:0031069 IEA hair follicle morphogenesis
GO:0031532 IDA actin cytoskeleton reorganization
GO:0034394 IDA protein localization to cell surface
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0042056 IDA chemoattractant activity
GO:0045087 TAS innate immune response
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048015 TAS phosphatidylinositol-mediated signaling
GO:0050679 IDA positive regulation of epithelial cell proliferation
GO:0050731 IDA positive regulation of peptidyl-tyrosine phosphorylation
GO:0050918 IDA positive chemotaxis
GO:0051549 IDA positive regulation of keratinocyte migration
GO:0051781 IEA positive regulation of cell division
GO:0060445 IEA branching involved in salivary gland morphogenesis
GO:0060501 IDA positive regulation of epithelial cell proliferation involved in lung morphogenesis
GO:0060665 IEA regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling
GO:0061033 IDA secretion by lung epithelial cell involved in lung growth

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059387 fgf7 fibroblast growth factor 7 protein_coding Danio_rerio
ENSMUSG00000027208 Fgf7 fibroblast growth factor 7 protein_coding Mus_musculus

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