C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cytochrome P450, family 11, subfamily A, polypeptide 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000140459 CYP11A1 9606 - 15:74337759-74367740 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000268053 CYP11A1-001 74337759-74367740 protein_coding
  ENST00000358632 CYP11A1-002 74337759-74366206 protein_coding
  ENST00000416978 CYP11A1-008 74345211-74367646 protein_coding
  ENST00000435365 CYP11A1-006 74337872-74367627 nonsense_mediated_decay
  ENST00000450547 CYP11A1-004 74343856-74366178 protein_coding
  ENST00000466978 CYP11A1-003 74345202-74366189 retained_intron
  ENST00000467407 CYP11A1-005 74361375-74367646 processed_transcript
  ENST00000498141 CYP11A1-007 74337780-74339315 retained_intron
  ENST00000566674 CYP11A1-011 74339587-74359603 protein_coding
  ENST00000569662 CYP11A1-010 74345115-74366158 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000268053ENST00000358632ENST00000435365ENST00000467407ENST00000498141ENST00000566674
Transcript ID Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000268053 N/A N/A N/A N/A N/A N/A N/A 30.196±24.95 40.947±0.00 N/A
ENST00000358632 0.287±0.24 N/A 0.549±0.00 0.207±0.00 0.170±0.00 0.192±0.00 0.310±0.00 148.344±142.07 14.572±0.00 4.578±0.00
ENST00000435365 N/A 1.218±0.00 N/A N/A N/A N/A N/A 72.908±0.00 10.483±0.00 N/A
ENST00000467407 N/A N/A N/A N/A N/A 0.276±0.00 N/A N/A N/A N/A
ENST00000498141 N/A N/A N/A N/A N/A N/A N/A 1.163±0.00 55.891±0.00 N/A
ENST00000566674 0.850±0.00 N/A N/A N/A 0.525±0.00 N/A 0.419±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007UD CIL_0007UD_0001 VISTA 15:74278506-74880453

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001101 IEA response to acid
GO:0004497 IEA monooxygenase activity
GO:0005506 IEA iron ion binding
GO:0005739 ISS mitochondrion
GO:0005743 IEA mitochondrial inner membrane
GO:0005759 TAS mitochondrial matrix
GO:0006082 IEA organic acid metabolic process
GO:0006694 IEA steroid biosynthetic process
GO:0006700 IDA C21-steroid hormone biosynthetic process
GO:0006701 IEA progesterone biosynthetic process
GO:0006703 IEA estrogen biosynthetic process
GO:0006805 TAS xenobiotic metabolic process
GO:0007584 IEA response to nutrient
GO:0007617 IEA mating behavior
GO:0008202 TAS steroid metabolic process
GO:0008203 ISS cholesterol metabolic process
GO:0008386 ISS cholesterol monooxygenase (side-chain-cleaving) activity
GO:0008584 IEA male gonad development
GO:0009651 IEA response to salt stress
GO:0010033 IEA response to organic substance
GO:0010212 IEA response to ionizing radiation
GO:0010332 IEA response to gamma radiation
GO:0014037 IEA Schwann cell differentiation
GO:0014070 IEA response to organic cyclic compound
GO:0015485 IEA cholesterol binding
GO:0016125 TAS sterol metabolic process
GO:0016705 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0017085 IEA response to insecticide
GO:0018879 IEA biphenyl metabolic process
GO:0018894 IEA dibenzo-p-dioxin metabolic process
GO:0018958 IEA phenol-containing compound metabolic process
GO:0018963 IEA phthalate metabolic process
GO:0020037 IEA:IDA heme binding
GO:0021549 IEA cerebellum development
GO:0021766 IEA hippocampus development
GO:0030061 IEA mitochondrial crista
GO:0033197 IEA response to vitamin E
GO:0033327 IEA Leydig cell differentiation
GO:0033591 IEA response to L-ascorbic acid
GO:0033595 IEA response to genistein
GO:0034698 IEA response to gonadotropin
GO:0042359 ISS vitamin D metabolic process
GO:0042493 IEA response to drug
GO:0042542 IEA response to hydrogen peroxide
GO:0043204 IEA perikaryon
GO:0043279 IEA response to alkaloid
GO:0043434 IEA response to peptide hormone
GO:0043627 IEA response to estrogen
GO:0044281 TAS small molecule metabolic process
GO:0044344 IEA cellular response to fibroblast growth factor stimulus
GO:0046677 IEA response to antibiotic
GO:0046686 IEA response to cadmium ion
GO:0048545 IEA response to steroid hormone
GO:0050756 IEA fractalkine metabolic process
GO:0051412 IEA response to corticosterone
GO:0051591 IEA response to cAMP
GO:0055114 IEA oxidation-reduction process
GO:0060014 IEA granulosa cell differentiation
GO:0060135 IEA maternal process involved in female pregnancy
GO:0060992 IEA response to fungicide
GO:0061370 IEA testosterone biosynthetic process
GO:0071222 IEA cellular response to lipopolysaccharide
GO:0071236 IEA cellular response to antibiotic
GO:0071276 IEA cellular response to cadmium ion
GO:0071320 IEA cellular response to cAMP
GO:0071347 IEA cellular response to interleukin-1
GO:0071356 IEA cellular response to tumor necrosis factor
GO:0071371 IEA cellular response to gonadotropin stimulus
GO:0071372 IEA cellular response to follicle-stimulating hormone stimulus
GO:0071375 IEA cellular response to peptide hormone stimulus
GO:0071560 IEA cellular response to transforming growth factor beta stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000002347 cyp11a1 cytochrome P450, subfamily XIA, polypeptide 1 protein_coding Danio_rerio
ENSDARG00000092696 CYP11A1 (2 of 2) cytochrome P450, family 11, subfamily A, polypeptide 1 protein_coding Danio_rerio
ENSMUSG00000032323 Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 protein_coding Mus_musculus

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