C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cytochrome P450, family 1, subfamily A, polypeptide 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000140465 CYP1A1 9606 - 15:74719542-74725610 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000379727 CYP1A1-001 74719542-74725610 protein_coding
  ENST00000395048 CYP1A1-201 74719542-74725536 protein_coding
  ENST00000395049 CYP1A1-003 74720430-74725494 protein_coding
  ENST00000562201 CYP1A1-007 74720720-74725491 nonsense_mediated_decay
  ENST00000564596 CYP1A1-004 74720720-74725491 protein_coding
  ENST00000566503 CYP1A1-006 74720720-74725491 protein_coding
  ENST00000567032 CYP1A1-002 74720156-74725370 protein_coding
  ENST00000569630 CYP1A1-005 74720720-74725491 nonsense_mediated_decay
  ENST00000612821 CYP1A1-202 74719542-74723097 protein_coding
  ENST00000617691 CYP1A1-203 74719542-74725536 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000379727ENST00000395048ENST00000395049ENST00000562201ENST00000564596ENST00000566503ENST00000567032ENST00000612821ENST00000617691
Transcript ID Adipose Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000379727 0.371±0.00 N/A N/A 0.485±0.00 1.787±0.00 N/A N/A 6.178±0.00 N/A N/A N/A N/A
ENST00000395048 1.441±0.00 N/A N/A N/A N/A 1.752±0.00 N/A N/A N/A N/A 0.054±0.00 0.346±0.00
ENST00000395049 N/A N/A 0.060±0.00 0.099±0.00 N/A 1.387±0.00 3.729±0.00 18.519±0.00 0.996±0.00 0.076±0.00 0.134±0.01 N/A
ENST00000562201 N/A N/A N/A 0.087±0.00 N/A N/A 5.458±0.00 24.111±0.00 N/A 0.038±0.00 N/A N/A
ENST00000564596 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.151±0.00 0.054±0.00 N/A
ENST00000566503 N/A N/A 0.069±0.00 1.036±0.00 2.078±0.00 2.040±0.00 N/A 26.055±0.00 1.939±0.00 N/A 0.083±0.00 N/A
ENST00000567032 N/A N/A N/A N/A N/A 0.525±0.00 N/A N/A N/A 0.010±0.00 N/A 0.091±0.00
ENST00000612821 0.444±0.00 N/A N/A 0.153±0.00 N/A N/A 1.275±0.00 0.423±0.00 N/A N/A 0.040±0.00 0.117±0.00
ENST00000617691 N/A 0.166±0.00 0.050±0.00 N/A N/A 0.351±0.00 N/A N/A 1.247±0.00 N/A 0.180±0.00 0.199±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007UD CIL_0007UD_0001 VISTA 15:74278506-74880453

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001666 IEA response to hypoxia
GO:0001889 IEA liver development
GO:0003824 IEA catalytic activity
GO:0004497 IEA monooxygenase activity
GO:0005506 IEA iron ion binding
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006778 IEA porphyrin-containing compound metabolic process
GO:0006805 TAS xenobiotic metabolic process
GO:0007568 IEA aging
GO:0008283 IEA cell proliferation
GO:0008395 IEA steroid hydroxylase activity
GO:0009308 IEA amine metabolic process
GO:0009404 IEA toxin metabolic process
GO:0009611 IEA response to wounding
GO:0009615 IEA response to virus
GO:0009624 IEA response to nematode
GO:0009635 IEA response to herbicide
GO:0009636 IEA response to toxic substance
GO:0009792 IEA embryo development ending in birth or egg hatching
GO:0009804 IEA coumarin metabolic process
GO:0009812 IEA flavonoid metabolic process
GO:0010033 IEA response to organic substance
GO:0010041 IEA response to iron(III) ion
GO:0014070 IEA response to organic cyclic compound
GO:0016491 IDA oxidoreductase activity
GO:0016679 IEA oxidoreductase activity, acting on diphenols and related substances as donors
GO:0016705 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016711 IEA flavonoid 3'-monooxygenase activity
GO:0016712 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
GO:0017143 IEA insecticide metabolic process
GO:0017144 IDA drug metabolic process
GO:0018894 IEA dibenzo-p-dioxin metabolic process
GO:0019341 IEA dibenzo-p-dioxin catabolic process
GO:0019369 TAS arachidonic acid metabolic process
GO:0019373 TAS epoxygenase P450 pathway
GO:0019825 TAS oxygen binding
GO:0019899 IEA enzyme binding
GO:0020037 IEA heme binding
GO:0032094 IEA response to food
GO:0032451 IEA demethylase activity
GO:0032496 IEA response to lipopolysaccharide
GO:0032502 IEA developmental process
GO:0033189 IEA response to vitamin A
GO:0035902 IEA response to immobilization stress
GO:0042359 IC vitamin D metabolic process
GO:0042493 IEA response to drug
GO:0042904 IEA 9-cis-retinoic acid biosynthetic process
GO:0043010 IEA camera-type eye development
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0046483 IEA heterocycle metabolic process
GO:0046677 IEA response to antibiotic
GO:0046685 IEA response to arsenic-containing substance
GO:0048565 IEA digestive tract development
GO:0050665 IEA hydrogen peroxide biosynthetic process
GO:0055093 IEA response to hyperoxia
GO:0055114 IEA:IDA oxidation-reduction process
GO:0060137 IEA maternal process involved in parturition
GO:0070330 IEA aromatase activity
GO:0070365 IEA hepatocyte differentiation
GO:0070576 IDA vitamin D 24-hydroxylase activity
GO:0070988 IEA demethylation
GO:0071407 IDA cellular response to organic cyclic compound
GO:0097267 TAS omega-hydroxylase P450 pathway
GO:1900087 IEA positive regulation of G1/S transition of mitotic cell cycle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000026039 cyp1a cytochrome P450, family 1, subfamily A protein_coding Danio_rerio
ENSMUSG00000032315 Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 protein_coding Mus_musculus

Loading