C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cytochrome P450, family 1, subfamily A, polypeptide 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000140505 CYP1A2 9606 + 15:74748844-74756202 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000343932 CYP1A2-001 74748844-74756202 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000343932
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000343932 0.125±0.00 0.318±0.00 0.083±0.06 0.160±0.03 0.166±0.00 0.051±0.00 34.427±34.30 3.028±2.93 0.464±0.00 0.012±0.00 0.067±0.04 0.083±0.07 0.142±0.05

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007UD CIL_0007UD_0001 VISTA 15:74278506-74880453

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004497 IDA monooxygenase activity
GO:0005506 IEA iron ion binding
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006706 IMP steroid catabolic process
GO:0006725 IEA cellular aromatic compound metabolic process
GO:0006778 IEA porphyrin-containing compound metabolic process
GO:0006805 TAS xenobiotic metabolic process
GO:0009055 TAS electron carrier activity
GO:0009403 IDA toxin biosynthetic process
GO:0009404 IEA toxin metabolic process
GO:0009791 IEA post-embryonic development
GO:0009820 IDA alkaloid metabolic process
GO:0010033 IEA response to organic substance
GO:0010468 IEA regulation of gene expression
GO:0014070 IEA response to organic cyclic compound
GO:0016098 IDA monoterpenoid metabolic process
GO:0016491 IDA oxidoreductase activity
GO:0016705 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016712 IMP oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
GO:0017144 IDA drug metabolic process
GO:0018894 IEA dibenzo-p-dioxin metabolic process
GO:0019369 TAS arachidonic acid metabolic process
GO:0019373 TAS epoxygenase P450 pathway
GO:0019899 IPI enzyme binding
GO:0020037 IDA:IEA heme binding
GO:0030324 IEA lung development
GO:0032259 TAS methylation
GO:0032355 IEA response to estradiol
GO:0032451 IDA demethylase activity
GO:0032496 IEA response to lipopolysaccharide
GO:0032787 IDA monocarboxylic acid metabolic process
GO:0034875 IDA caffeine oxidase activity
GO:0035902 IEA response to immobilization stress
GO:0042493 IEA response to drug
GO:0042737 IMP drug catabolic process
GO:0042738 IDA exogenous drug catabolic process
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0044281 TAS small molecule metabolic process
GO:0045333 IEA cellular respiration
GO:0046483 IDA heterocycle metabolic process
GO:0050665 IEA hydrogen peroxide biosynthetic process
GO:0055114 IDA:IEA oxidation-reduction process
GO:0070330 IEA aromatase activity
GO:0070989 IDA oxidative demethylation
GO:0071276 IEA cellular response to cadmium ion
GO:0071615 IDA oxidative deethylation
GO:0097267 TAS omega-hydroxylase P450 pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000026039 cyp1a cytochrome P450, family 1, subfamily A protein_coding Danio_rerio
ENSMUSG00000032310 Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 protein_coding Mus_musculus

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