C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: polymerase (DNA directed), gamma
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000140521 POLG 9606 - 15:89316303-89334861 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000268124 POLG-001 89316303-89334847 protein_coding
  ENST00000442287 POLG-002 89316320-89334861 protein_coding
  ENST00000525806 POLG-011 89332329-89333244 processed_transcript
  ENST00000526314 POLG-013 89322742-89326691 protein_coding
  ENST00000526398 POLG-005 89322805-89325587 nonsense_mediated_decay
  ENST00000526573 POLG-006 89323514-89325484 retained_intron
  ENST00000526671 POLG-010 89316517-89317828 retained_intron
  ENST00000528881 POLG-012 89320820-89323437 nonsense_mediated_decay
  ENST00000530292 POLG-009 89316339-89320830 nonsense_mediated_decay
  ENST00000530715 POLG-008 89319268-89323427 nonsense_mediated_decay
  ENST00000532363 POLG-003 89327013-89328698 retained_intron
  ENST00000532584 POLG-004 89321775-89325600 retained_intron
  ENST00000533857 POLG-007 89323520-89324291 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000268124ENST00000442287ENST00000526398ENST00000530292
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000268124 N/A N/A 1.546±0.57 N/A N/A N/A N/A 1.898±0.34 4.175±3.03 7.148±0.00 4.850±0.64 3.621±0.00 N/A
ENST00000442287 11.887±0.00 11.540±0.00 5.772±0.00 4.465±2.42 5.811±4.14 9.991±0.00 10.963±0.00 2.413±0.00 4.304±0.00 4.446±0.00 5.598±1.49 7.950±2.68 5.484±0.00
ENST00000526398 N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.998±0.00 N/A N/A N/A
ENST00000530292 10.503±0.00 20.751±0.00 7.318±0.00 N/A 9.299±0.00 N/A 10.135±0.00 4.539±0.00 N/A N/A 19.771±11.02 16.589±0.00 16.028±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00011C CIL_00011C_0001 CGP 15:89209869-89317261
CIL_0002RC CIL_0002RC_0002 CGP 15:89243949-89334861
CIL_0002R9 CIL_0002R9_0002 CGP 15:89316303-89496613

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002020 IPI protease binding
GO:0003676 IEA nucleic acid binding
GO:0003677 IEA DNA binding
GO:0003682 IDA chromatin binding
GO:0003887 IDA:IEA DNA-directed DNA polymerase activity
GO:0004527 IEA exonuclease activity
GO:0005515 IPI protein binding
GO:0005739 TAS mitochondrion
GO:0005743 IEA mitochondrial inner membrane
GO:0005760 IEA gamma DNA polymerase complex
GO:0006259 TAS DNA metabolic process
GO:0006260 IEA DNA replication
GO:0006261 TAS:IEA DNA-dependent DNA replication
GO:0006264 IEA mitochondrial DNA replication
GO:0006287 IDA base-excision repair, gap-filling
GO:0007568 IEA aging
GO:0008219 IEA cell death
GO:0042645 IDA mitochondrial nucleoid
GO:0070062 IDA extracellular vesicular exosome
GO:0071897 IEA DNA biosynthetic process
GO:0090305 IEA nucleic acid phosphodiester bond hydrolysis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000060951 polg polymerase (DNA directed), gamma protein_coding Danio_rerio
ENSMUSG00000039176 Polg polymerase (DNA directed), gamma protein_coding Mus_musculus

Loading