C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: TOPBP1-interacting checkpoint and replication regulator
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000140534 TICRR 9606 + 15:89575482-89631056 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000268138 TICRR-001 89575482-89628023 protein_coding
  ENST00000560985 TICRR-003 89575587-89628012 protein_coding
  ENST00000561095 TICRR-002 89625400-89631056 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000268138ENST00000560985ENST00000561095
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000268138 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.512±0.07 0.377±0.12 N/A
ENST00000560985 0.207±0.00 0.478±0.00 N/A 0.064±0.04 0.144±0.00 0.488±0.00 0.047±0.01 N/A 0.063±0.05 0.053±0.00 0.475±0.07 0.269±0.11 1.057±0.08
ENST00000561095 N/A N/A 0.051±0.00 0.112±0.00 N/A N/A N/A 0.174±0.00 N/A 0.144±0.00 1.719±0.00 0.347±0.00 0.998±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00011D CIL_00011D_0001 CGP 15:89471398-89631056
CIL_00008C CIL_00008C_0001 CGP 15:89575482-89655451

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000075 ISS cell cycle checkpoint
GO:0001731 ISS formation of translation preinitiation complex
GO:0003682 IDA chromatin binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006260 ISS DNA replication
GO:0006281 ISS DNA repair
GO:0010212 ISS response to ionizing radiation
GO:0030174 IMP regulation of DNA-dependent DNA replication initiation
GO:0033314 ISS mitotic DNA replication checkpoint

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000046591 Ticrr TOPBP1-interacting checkpoint and replication regulator protein_coding Mus_musculus

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