C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ADAM metallopeptidase with thrombospondin type 1 motif, 18
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000140873 ADAMTS18 9606 - 16:77247813-77435114 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000282849 ADAMTS18-001 77282128-77435114 protein_coding
  ENST00000449265 ADAMTS18-002 77355951-77435034 nonsense_mediated_decay
  ENST00000562332 ADAMTS18-011 77247813-77289359 protein_coding
  ENST00000562345 ADAMTS18-009 77364352-77431587 protein_coding
  ENST00000564369 ADAMTS18-005 77367571-77434521 processed_transcript
  ENST00000567121 ADAMTS18-006 77367483-77432448 processed_transcript
  ENST00000567914 ADAMTS18-008 77367437-77431633 retained_intron
  ENST00000568393 ADAMTS18-010 77300039-77321136 retained_intron
  ENST00000569309 ADAMTS18-007 77367610-77431746 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartLiverLungMuscleOvaryPlacentaENST00000282849ENST00000449265ENST00000562345
Transcript ID Adipose Bladder Brain Breast Colon Heart Liver Lung Muscle Ovary Placenta
ENST00000282849 0.590±0.00 0.017±0.00 2.290±0.00 N/A 0.033±0.00 0.007±0.00 0.007±0.00 0.012±0.00 0.009±0.00 0.280±0.00 3.332±0.27
ENST00000449265 N/A N/A N/A N/A N/A N/A 0.170±0.00 N/A N/A N/A N/A
ENST00000562345 N/A N/A N/A 1.431±0.00 N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003OG CIL_0003OG_0001 CGP 16:77199397-77435114
CIL_0003OF CIL_0003OF_0001 CGP 16:77247813-77742260

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001654 IMP eye development
GO:0004222 IEA metalloendopeptidase activity
GO:0005578 IEA proteinaceous extracellular matrix
GO:0006508 IEA proteolysis
GO:0007229 IEA integrin-mediated signaling pathway
GO:0008233 IEA peptidase activity
GO:0008270 IEA zinc ion binding
GO:0031012 IEA extracellular matrix
GO:0090331 IDA negative regulation of platelet aggregation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000001999 adamts18 ADAM metallopeptidase with thrombospondin type 1 motif, 18 protein_coding Danio_rerio
ENSMUSG00000053399 Adamts18 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 18 protein_coding Mus_musculus

Loading