C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: membrane-bound transcription factor peptidase, site 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000140943 MBTPS1 9606 - 16:84053761-84116906 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000343411 MBTPS1-001 84053766-84116906 protein_coding
  ENST00000561936 MBTPS1-017 84059303-84061217 retained_intron
  ENST00000562788 MBTPS1-014 84081522-84085026 protein_coding
  ENST00000562886 MBTPS1-006 84053774-84061631 retained_intron
  ENST00000562906 MBTPS1-007 84053761-84058044 retained_intron
  ENST00000563231 MBTPS1-012 84070764-84091786 nonsense_mediated_decay
  ENST00000564049 MBTPS1-018 84059302-84061148 retained_intron
  ENST00000564444 MBTPS1-010 84101898-84116818 processed_transcript
  ENST00000564643 MBTPS1-019 84070598-84082169 retained_intron
  ENST00000565863 MBTPS1-013 84075523-84090920 processed_transcript
  ENST00000567557 MBTPS1-008 84101801-84116835 processed_transcript
  ENST00000568051 MBTPS1-016 84070019-84072137 processed_transcript
  ENST00000569770 MBTPS1-015 84070715-84093286 processed_transcript
  ENST00000569907 MBTPS1-009 84101735-84116835 protein_coding
  ENST00000570012 MBTPS1-011 84085054-84116795 protein_coding
  ENST00000570064 MBTPS1-005 84053766-84075433 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000343411ENST00000562886ENST00000562906ENST00000570012ENST00000570064
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000343411 23.608±0.00 13.413±0.00 3.691±0.00 7.522±2.56 15.998±13.18 9.749±3.37 12.426±9.66 9.462±5.33 6.352±2.55 8.360±1.71 3.019±2.13 15.883±10.68 11.391±3.21 12.145±0.82
ENST00000562886 N/A N/A N/A 2.606±0.00 N/A 1.901±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000562906 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.174±0.00 N/A N/A N/A
ENST00000570012 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 18.475±0.00 N/A N/A
ENST00000570064 N/A N/A N/A N/A 1.540±0.00 N/A N/A N/A N/A N/A N/A 6.654±0.00 10.477±0.00 8.258±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00057A CIL_00057A_0002 CGP 16:84009667-84116906
CIL_0002AP CIL_0002AP_0001 CGP 16:84053761-84145192

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000139 TAS Golgi membrane
GO:0004175 IEA endopeptidase activity
GO:0004252 IBA:IEA serine-type endopeptidase activity
GO:0005788 TAS endoplasmic reticulum lumen
GO:0005794 IBA Golgi apparatus
GO:0005795 IEA Golgi stack
GO:0006508 IEA:IBA proteolysis
GO:0006629 IBA lipid metabolic process
GO:0006987 TAS activation of signaling protein activity involved in unfolded protein response
GO:0007040 IMP lysosome organization
GO:0008203 IEA cholesterol metabolic process
GO:0016021 IEA integral component of membrane
GO:0030968 TAS endoplasmic reticulum unfolded protein response
GO:0042990 IEA regulation of transcription factor import into nucleus
GO:0044267 TAS cellular protein metabolic process
GO:0044281 TAS small molecule metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014634 mbtps1 membrane-bound transcription factor protease, site 1 protein_coding Danio_rerio
ENSMUSG00000031835 Mbtps1 membrane-bound transcription factor peptidase, site 1 protein_coding Mus_musculus

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