C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: adenylate cyclase activating polypeptide 1 (pituitary)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000141433 ADCYAP1 9606 + 18:904943-912172 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000269200 ADCYAP1-005 907551-909670 retained_intron
  ENST00000450565 ADCYAP1-002 904943-909903 protein_coding
  ENST00000579794 ADCYAP1-003 905109-912172 protein_coding
  ENST00000581602 ADCYAP1-004 908032-911025 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000269200ENST00000450565ENST00000579794ENST00000581602
Transcript ID Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000269200 N/A 4.503±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000450565 N/A N/A N/A N/A N/A N/A 0.049±0.00 N/A N/A 0.059±0.00 N/A
ENST00000579794 N/A 1.043±0.64 0.024±0.00 0.065±0.00 0.032±0.00 N/A 0.020±0.00 0.110±0.00 0.084±0.04 0.024±0.01 0.960±0.00
ENST00000581602 0.032±0.00 1.412±0.00 N/A 0.209±0.00 N/A 0.137±0.00 N/A 0.043±0.00 0.039±0.01 0.056±0.00 1.359±0.67

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00025N CIL_00025N_0002 CGP 18:721588-912172
CIL_00025O CIL_00025O_0002 CGP 18:904943-2571509

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001541 IEA ovarian follicle development
GO:0001662 IEA behavioral fear response
GO:0001821 IEA histamine secretion
GO:0002865 IEA negative regulation of acute inflammatory response to antigenic stimulus
GO:0002878 IEA negative regulation of acute inflammatory response to non-antigenic stimulus
GO:0005057 IEA receptor signaling protein activity
GO:0005102 IPI receptor binding
GO:0005179 IEA hormone activity
GO:0005184 IDA neuropeptide hormone activity
GO:0005576 TAS:IEA extracellular region
GO:0005615 IEA extracellular space
GO:0007169 TAS transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007190 TAS activation of adenylate cyclase activity
GO:0007204 IEA positive regulation of cytosolic calcium ion concentration
GO:0007218 IDA neuropeptide signaling pathway
GO:0007267 TAS cell-cell signaling
GO:0007565 TAS female pregnancy
GO:0008277 IDA regulation of G-protein coupled receptor protein signaling pathway
GO:0008284 IEA positive regulation of cell proliferation
GO:0010579 IDA positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway
GO:0010628 IEA positive regulation of gene expression
GO:0010656 IEA negative regulation of muscle cell apoptotic process
GO:0010976 IEA positive regulation of neuron projection development
GO:0016521 IDA pituitary adenylate cyclase activating polypeptide activity
GO:0019233 IEA sensory perception of pain
GO:0019933 IMP cAMP-mediated signaling
GO:0021983 IEA pituitary gland development
GO:0030819 IEA positive regulation of cAMP biosynthetic process
GO:0031175 IDA neuron projection development
GO:0031858 IEA pituitary adenylate cyclase-activating polypeptide receptor binding
GO:0032755 IEA positive regulation of interleukin-6 production
GO:0032854 IDA positive regulation of Rap GTPase activity
GO:0032880 IDA regulation of protein localization
GO:0034259 IEA negative regulation of Rho GTPase activity
GO:0042594 IEA response to starvation
GO:0043195 IEA terminal bouton
GO:0043267 IEA negative regulation of potassium ion transport
GO:0045471 IEA response to ethanol
GO:0045786 IEA negative regulation of cell cycle
GO:0045860 IDA positive regulation of protein kinase activity
GO:0045909 IEA positive regulation of vasodilation
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046034 IEA ATP metabolic process
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0051428 IDA peptide hormone receptor binding
GO:0051968 IEA positive regulation of synaptic transmission, glutamatergic
GO:0060078 IEA regulation of postsynaptic membrane potential
GO:0060124 IEA positive regulation of growth hormone secretion
GO:0060253 IEA negative regulation of glial cell proliferation
GO:0070374 IDA positive regulation of ERK1 and ERK2 cascade
GO:0070445 IEA regulation of oligodendrocyte progenitor proliferation
GO:0071385 IEA cellular response to glucocorticoid stimulus
GO:0090274 IEA positive regulation of somatostatin secretion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004015 adcyap1a adenylate cyclase activating polypeptide 1a protein_coding Danio_rerio
ENSDARG00000027740 adcyap1b adenylate cyclase activating polypeptide 1b protein_coding Danio_rerio
ENSMUSG00000024256 Adcyap1 adenylate cyclase activating polypeptide 1 protein_coding Mus_musculus

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