C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: calpain 10
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000142330 CAPN10 9606 + 2:240586716-240617705 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000270361 CAPN10-008 240586871-240599084 nonsense_mediated_decay
  ENST00000270364 CAPN10-006 240586772-240617705 protein_coding
  ENST00000352879 CAPN10-002 240586871-240599084 protein_coding
  ENST00000354082 CAPN10-007 240586871-240599084 protein_coding
  ENST00000357048 CAPN10-003 240586871-240599084 nonsense_mediated_decay
  ENST00000391983 CAPN10-009 240586871-240599109 nonsense_mediated_decay
  ENST00000391984 CAPN10-001 240586716-240599109 protein_coding
  ENST00000404753 CAPN10-005 240586739-240599104 protein_coding
  ENST00000416591 CAPN10-004 240586871-240599084 nonsense_mediated_decay
  ENST00000426297 CAPN10-016 240598024-240607520 nonsense_mediated_decay
  ENST00000432084 CAPN10-017 240590992-240592878 protein_coding
  ENST00000463653 CAPN10-012 240586734-240589810 retained_intron
  ENST00000465943 CAPN10-013 240594241-240595103 retained_intron
  ENST00000483602 CAPN10-014 240595146-240596702 retained_intron
  ENST00000493058 CAPN10-015 240595234-240598399 retained_intron
  ENST00000494738 CAPN10-010 240589884-240599103 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000270361ENST00000352879ENST00000354082ENST00000391983ENST00000391984ENST00000404753ENST00000416591ENST00000426297ENST00000432084ENST00000463653ENST00000483602ENST00000494738
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000270361 1.528±0.00 N/A N/A 2.143±0.00 2.158±0.00 4.837±0.00 3.247±0.00 8.959±0.00 2.002±0.00 3.823±0.00 N/A 5.415±0.00 2.047±0.43 4.866±0.00
ENST00000352879 N/A N/A N/A 1.890±1.35 N/A N/A 3.223±0.00 N/A 1.851±0.00 4.416±0.00 0.902±0.00 N/A N/A N/A
ENST00000354082 N/A 3.064±0.00 N/A N/A N/A N/A N/A N/A N/A 0.561±0.00 N/A 2.458±0.00 1.166±0.33 N/A
ENST00000391983 N/A N/A 0.227±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000391984 N/A 2.031±0.00 N/A 0.228±0.00 N/A N/A 1.463±0.00 N/A N/A N/A N/A 5.495±1.91 1.614±0.20 4.923±0.00
ENST00000404753 0.488±0.00 N/A 0.137±0.00 N/A 1.461±0.53 N/A 1.896±0.00 N/A 0.246±0.00 N/A 0.544±0.00 N/A N/A 2.733±0.00
ENST00000416591 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.245±0.00 N/A 0.585±0.18 1.738±0.00
ENST00000426297 N/A N/A 0.793±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000432084 N/A N/A N/A N/A N/A N/A N/A 0.672±0.00 N/A N/A N/A N/A N/A N/A
ENST00000463653 N/A N/A N/A N/A N/A N/A N/A 1.385±0.00 0.433±0.00 N/A N/A N/A N/A N/A
ENST00000483602 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.958±0.00 N/A N/A N/A
ENST00000494738 N/A N/A N/A N/A N/A N/A 0.247±0.00 0.074±0.00 N/A N/A N/A N/A N/A 1.780±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009AE CIL_0009AE_0001 VISTA 2:240068562-240673577
CIL_0003NU CIL_0003NU_0001 CGP 2:240565804-240617705
CIL_0003NA CIL_0003NA_0001 CGP 2:240586716-240631259

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000149 ISS SNARE binding
GO:0004198 IMP:IEA calcium-dependent cysteine-type endopeptidase activity
GO:0005622 IEA intracellular
GO:0005623 IDA cell
GO:0005739 IDA mitochondrion
GO:0005829 ISS cytosol
GO:0005886 ISS plasma membrane
GO:0006508 IMP:IEA proteolysis
GO:0006921 IC cellular component disassembly involved in execution phase of apoptosis
GO:0008092 ISS cytoskeletal protein binding
GO:0031532 ISS actin cytoskeleton reorganization
GO:0032024 IMP positive regulation of insulin secretion
GO:0032388 ISS positive regulation of intracellular transport
GO:0032869 IMP cellular response to insulin stimulus
GO:0046326 IMP positive regulation of glucose import
GO:0097050 IDA type B pancreatic cell apoptotic process
GO:2000676 IEA positive regulation of type B pancreatic cell apoptotic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076634 capn10 calpain 10 protein_coding Danio_rerio
ENSMUSG00000026270 Capn10 calpain 10 protein_coding Mus_musculus

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