C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SH3 domain binding glutamate-rich protein like 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000142669 SH3BGRL3 9606 + 1:26279176-26281522 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000270792 SH3BGRL3-001 26279176-26281522 protein_coding
  ENST00000319041 SH3BGRL3-002 26280122-26281450 protein_coding
  ENST00000614679 SH3BGRL3-201 26279176-26281516 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000270792ENST00000319041ENST00000614679
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000270792 N/A N/A N/A 9.688±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000319041 156.477±0.00 248.178±0.00 N/A 55.223±0.00 119.367±0.00 104.091±0.00 33.015±0.00 96.462±0.00 29.946±27.55 247.638±0.00 18.280±0.00 104.977±0.18 158.605±54.37 135.713±0.00
ENST00000614679 28.706±0.00 45.908±0.00 0.935±0.00 6.733±2.92 12.081±10.26 12.076±10.96 0.563±0.00 8.915±6.62 6.601±0.00 2.183±0.00 1.648±0.68 58.471±31.78 46.538±20.09 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005100 IMP Rho GTPase activator activity
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0009055 IEA electron carrier activity
GO:0015035 IEA protein disulfide oxidoreductase activity
GO:0030027 IDA lamellipodium
GO:0030215 IPI semaphorin receptor binding
GO:0030834 IMP regulation of actin filament depolymerization
GO:0032321 IMP positive regulation of Rho GTPase activity
GO:0032956 IMP regulation of actin cytoskeleton organization
GO:0043535 IMP regulation of blood vessel endothelial cell migration
GO:0045454 IEA cell redox homeostasis
GO:0055114 IEA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000036016 sh3bgrl3 SH3 domain binding glutamic acid-rich protein like 3 protein_coding Danio_rerio
ENSMUSG00000028843 Sh3bgrl3 SH3 domain binding glutamic acid-rich protein-like 3 protein_coding Mus_musculus

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