C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: connector enhancer of kinase suppressor of Ras 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000142675 CNKSR1 9606 + 1:26177403-26189886 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000361530 CNKSR1-001 26177403-26189886 protein_coding
  ENST00000374253 CNKSR1-007 26177509-26189884 protein_coding
  ENST00000465415 CNKSR1-004 26177503-26181083 retained_intron
  ENST00000480348 CNKSR1-010 26177490-26183218 processed_transcript
  ENST00000480617 CNKSR1-005 26186915-26188301 retained_intron
  ENST00000481077 CNKSR1-008 26177484-26183795 nonsense_mediated_decay
  ENST00000482227 CNKSR1-002 26177512-26189882 nonsense_mediated_decay
  ENST00000484874 CNKSR1-006 26187293-26188853 retained_intron
  ENST00000524529 CNKSR1-012 26181587-26183256 retained_intron
  ENST00000525687 CNKSR1-011 26177512-26185041 nonsense_mediated_decay
  ENST00000528001 CNKSR1-014 26182055-26184409 processed_transcript
  ENST00000528281 CNKSR1-015 26183204-26188457 nonsense_mediated_decay
  ENST00000531150 CNKSR1-013 26182005-26184195 retained_intron
  ENST00000531191 CNKSR1-003 26180168-26189846 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000361530ENST00000374253ENST00000465415ENST00000480617ENST00000481077ENST00000482227ENST00000524529ENST00000525687ENST00000528281ENST00000531150ENST00000531191
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000361530 N/A N/A N/A N/A N/A N/A N/A 0.616±0.00 N/A N/A N/A 6.203±4.56 3.903±0.00 0.338±0.04
ENST00000374253 N/A N/A N/A 0.133±0.00 N/A N/A N/A 1.445±0.00 0.045±0.00 1.032±0.74 2.169±0.00 3.659±3.08 3.838±0.85 N/A
ENST00000465415 N/A 0.766±0.00 N/A N/A 0.962±0.00 N/A 0.355±0.00 N/A 0.373±0.00 N/A N/A N/A N/A N/A
ENST00000480617 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.786±0.00 N/A N/A N/A N/A
ENST00000481077 N/A N/A N/A N/A N/A N/A 0.131±0.00 N/A N/A N/A N/A 1.344±0.00 N/A N/A
ENST00000482227 0.224±0.00 0.319±0.00 0.256±0.00 0.157±0.00 N/A N/A N/A N/A N/A 1.135±0.00 N/A N/A 3.675±0.00 0.287±0.00
ENST00000524529 N/A N/A N/A N/A N/A 2.328±0.00 N/A N/A N/A 1.123±0.00 N/A N/A N/A N/A
ENST00000525687 N/A N/A N/A 0.179±0.00 N/A N/A N/A N/A N/A N/A N/A 0.461±0.00 N/A N/A
ENST00000528281 N/A N/A N/A 0.103±0.00 N/A N/A N/A N/A 0.119±0.00 N/A N/A 2.256±0.00 2.693±0.00 N/A
ENST00000531150 N/A N/A N/A N/A 1.961±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000531191 N/A 0.125±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.381±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005886 TAS plasma membrane
GO:0005911 TAS cell-cell junction
GO:0005938 IDA cell cortex
GO:0007169 TAS transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007265 IPI Ras protein signal transduction
GO:0007266 IPI Rho protein signal transduction
GO:0016301 IEA kinase activity
GO:0016310 IEA phosphorylation
GO:0030674 IDA protein binding, bridging

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000032932 cnksr1 connector enhancer of kinase suppressor of Ras 1 protein_coding Danio_rerio
ENSMUSG00000028841 Cnksr1 connector enhancer of kinase suppressor of Ras 1 protein_coding Mus_musculus

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