C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mitogen-activated protein kinase kinase kinase 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000142733 MAP3K6 9606 - 1:27355184-27366892 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000357582 MAP3K6-007 27355391-27366866 protein_coding
  ENST00000374040 MAP3K6-008 27355186-27366858 protein_coding
  ENST00000470890 MAP3K6-004 27355356-27357167 retained_intron
  ENST00000472410 MAP3K6-002 27355184-27363951 protein_coding
  ENST00000476509 MAP3K6-005 27356590-27357614 retained_intron
  ENST00000486046 MAP3K6-006 27355184-27356471 protein_coding
  ENST00000493901 MAP3K6-001 27355189-27366892 protein_coding
  ENST00000495230 MAP3K6-003 27357161-27357808 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000357582ENST00000374040ENST00000470890ENST00000472410ENST00000486046ENST00000493901
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000357582 28.230±0.00 11.588±0.00 N/A 0.570±0.00 9.177±0.00 2.532±0.00 6.466±0.00 7.254±0.00 0.922±0.00 11.851±0.00 1.944±0.00 6.567±0.00 1.875±0.00 4.782±0.00
ENST00000374040 N/A N/A N/A N/A N/A 0.407±0.00 5.013±0.00 N/A 0.771±0.00 N/A N/A 2.487±2.02 2.680±1.74 N/A
ENST00000470890 N/A N/A 0.685±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.409±0.00
ENST00000472410 11.596±0.00 11.193±0.00 0.579±0.00 0.112±0.00 N/A 0.303±0.00 N/A 5.661±0.00 N/A 5.581±0.00 0.486±0.32 1.364±0.00 2.084±0.00 1.782±0.98
ENST00000486046 N/A N/A N/A 0.576±0.00 N/A N/A N/A N/A N/A 25.815±0.00 3.331±0.94 15.347±0.00 3.821±0.00 N/A
ENST00000493901 N/A N/A N/A N/A 0.491±0.00 N/A 4.681±0.00 4.058±0.00 1.167±0.00 2.415±1.24 1.635±0.00 2.379±1.97 1.728±0.00 0.767±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008WN CIL_0008WN_0001 VISTA 1:27203963-27805666

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000186 IEA activation of MAPKK activity
GO:0000287 IDA magnesium ion binding
GO:0004672 IEA protein kinase activity
GO:0004709 IDA MAP kinase kinase kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005524 IDA:IEA ATP binding
GO:0006468 IDA:IEA protein phosphorylation
GO:0007165 TAS signal transduction
GO:0007257 TAS activation of JUN kinase activity
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000069933 MAP3K6 mitogen-activated protein kinase kinase kinase 6 protein_coding Danio_rerio
ENSMUSG00000028862 Map3k6 mitogen-activated protein kinase kinase kinase 6 protein_coding Mus_musculus

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