C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: metal response element binding transcription factor 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000143033 MTF2 9606 + 1:93079235-93139081 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000370298 MTF2-001 93079238-93139081 protein_coding
  ENST00000370303 MTF2-003 93079311-93137151 protein_coding
  ENST00000467953 MTF2-007 93110246-93137132 processed_transcript
  ENST00000468457 MTF2-010 93118345-93120274 retained_intron
  ENST00000471953 MTF2-002 93079310-93137089 processed_transcript
  ENST00000473430 MTF2-006 93079283-93119401 processed_transcript
  ENST00000474314 MTF2-011 93079270-93115492 processed_transcript
  ENST00000476037 MTF2-008 93120793-93136852 processed_transcript
  ENST00000487263 MTF2-009 93120799-93134459 processed_transcript
  ENST00000489480 MTF2-004 93128795-93137132 processed_transcript
  ENST00000494963 MTF2-005 93079296-93119338 processed_transcript
  ENST00000497976 MTF2-012 93110424-93133740 processed_transcript
  ENST00000540243 MTF2-201 93079235-93139079 protein_coding
  ENST00000545708 MTF2-202 93079235-93139079 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000370298ENST00000370303ENST00000467953ENST00000471953ENST00000473430ENST00000476037ENST00000489480ENST00000494963ENST00000497976ENST00000540243ENST00000545708
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000370298 N/A N/A N/A N/A N/A N/A 0.880±0.00 N/A 0.602±0.00 0.785±0.00 N/A 1.827±0.05 2.068±0.27 4.286±0.00
ENST00000370303 0.979±0.00 N/A 0.504±0.00 1.789±0.00 2.162±1.09 2.368±0.00 0.592±0.00 N/A 1.175±0.70 N/A 0.940±0.00 1.914±0.65 2.452±0.00 4.278±0.00
ENST00000467953 N/A N/A N/A 2.044±0.00 N/A N/A 0.344±0.00 N/A N/A N/A 0.127±0.00 2.604±0.00 3.527±0.00 7.081±0.00
ENST00000471953 N/A 2.700±0.00 N/A N/A N/A 0.789±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000473430 N/A N/A N/A N/A N/A 4.194±0.00 N/A 1.301±0.00 N/A N/A N/A N/A N/A N/A
ENST00000476037 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.003±0.00 8.889±0.00 11.825±0.00
ENST00000489480 N/A N/A 1.262±0.00 1.329±0.00 2.554±0.00 3.958±0.00 0.505±0.00 1.086±0.00 1.429±0.00 4.724±0.00 N/A 5.998±0.00 N/A 9.567±0.00
ENST00000494963 N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.530±0.00 N/A N/A N/A N/A
ENST00000497976 N/A N/A N/A N/A N/A N/A N/A 2.309±0.00 N/A N/A N/A N/A N/A N/A
ENST00000540243 N/A N/A N/A 0.429±0.00 0.587±0.00 0.720±0.00 0.287±0.00 0.707±0.00 0.382±0.12 N/A 0.536±0.00 3.216±0.00 3.801±0.00 6.248±0.00
ENST00000545708 N/A N/A N/A N/A N/A N/A N/A N/A 0.254±0.00 N/A N/A N/A 0.605±0.00 2.885±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005ZP CIL_0005ZP_0001 CGP 1:92832737-93139081
CIL_0005ZQ CIL_0005ZQ_0001 CGP 1:93079235-93180728

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0003677 IEA DNA binding
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0007379 ISS segment specification
GO:0008270 IEA zinc ion binding
GO:0016568 IEA chromatin modification
GO:0019827 ISS stem cell maintenance
GO:0035064 IDA methylated histone binding
GO:0035098 ISS ESC/E(Z) complex
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0048863 ISS stem cell differentiation
GO:0061086 ISS negative regulation of histone H3-K27 methylation
GO:0061087 ISS positive regulation of histone H3-K27 methylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005590 mtf2 metal response element binding transcription factor 2 protein_coding Danio_rerio
ENSMUSG00000029267 Mtf2 metal response element binding transcription factor 2 protein_coding Mus_musculus

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