C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cathepsin K
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000143387 CTSK 9606 - 1:150796208-150808323 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000271651 CTSK-001 150796208-150808323 protein_coding
  ENST00000443913 CTSK-002 150804041-150807434 protein_coding
  ENST00000480670 CTSK-003 150804012-150806768 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000271651ENST00000443913ENST00000480670
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000271651 133.239±0.00 18.647±0.00 0.798±0.00 1.244±0.32 27.686±6.94 37.688±35.45 3.228±2.79 2.620±1.40 5.974±4.83 13.458±9.92 8.243±0.00 33.723±21.81 19.254±7.63 22.245±14.31
ENST00000443913 N/A N/A N/A N/A N/A N/A N/A 0.745±0.00 N/A N/A N/A N/A N/A N/A
ENST00000480670 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 26.587±0.00 27.113±0.00 8.882±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001957 IEA intramembranous ossification
GO:0001968 IPI fibronectin binding
GO:0002224 TAS toll-like receptor signaling pathway
GO:0004197 IDA:IEA cysteine-type endopeptidase activity
GO:0005518 IDA collagen binding
GO:0005576 TAS extracellular region
GO:0005615 IDA extracellular space
GO:0005737 IEA cytoplasm
GO:0005764 IEA lysosome
GO:0006508 TAS:IEA proteolysis
GO:0008234 TAS:IEA cysteine-type peptidase activity
GO:0022617 TAS extracellular matrix disassembly
GO:0030198 TAS extracellular matrix organization
GO:0030574 IDA collagen catabolic process
GO:0036021 TAS endolysosome lumen
GO:0043394 IPI proteoglycan binding
GO:0045087 TAS innate immune response
GO:0045453 IEA bone resorption
GO:0051603 IDA proteolysis involved in cellular protein catabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000040251 ctsk cathepsin K protein_coding Danio_rerio
ENSMUSG00000028111 Ctsk cathepsin K protein_coding Mus_musculus

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