C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: eukaryotic translation initiation factor 2D
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000143486 EIF2D 9606 - 1:206571292-206612463 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000271764 EIF2D-001 206591642-206612459 protein_coding
  ENST00000367114 EIF2D-002 206591642-206612459 protein_coding
  ENST00000437518 EIF2D-009 206602342-206612450 protein_coding
  ENST00000461334 EIF2D-006 206603083-206608295 processed_transcript
  ENST00000468891 EIF2D-011 206595831-206599810 retained_intron
  ENST00000472709 EIF2D-005 206571292-206597116 nonsense_mediated_decay
  ENST00000474408 EIF2D-008 206609376-206612459 processed_transcript
  ENST00000484492 EIF2D-007 206595718-206602958 nonsense_mediated_decay
  ENST00000613435 EIF2D-010 206595710-206609404 nonsense_mediated_decay
  ENST00000617960 EIF2D-004 206594040-206603501 retained_intron
  ENST00000620382 EIF2D-003 206604733-206612463 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000271764ENST00000367114ENST00000468891ENST00000617960
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000271764 12.366±0.00 16.083±0.00 1.397±0.00 3.290±1.94 10.161±7.53 10.587±7.02 4.240±3.39 9.155±5.77 6.968±2.67 4.693±0.71 8.417±4.99 14.296±10.80 16.714±6.49 11.160±4.72
ENST00000367114 N/A N/A N/A N/A N/A N/A 0.337±0.00 N/A N/A N/A 1.135±0.00 N/A 3.790±0.00 5.510±0.00
ENST00000468891 N/A N/A 4.353±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000617960 N/A N/A N/A N/A 0.499±0.22 0.308±0.00 0.255±0.13 N/A N/A 0.344±0.00 N/A 0.964±0.16 N/A 0.912±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001731 IDA formation of translation preinitiation complex
GO:0002192 IDA IRES-dependent translational initiation
GO:0003723 IEA RNA binding
GO:0003743 IDA:IEA translation initiation factor activity
GO:0004872 TAS receptor activity
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006413 IEA translational initiation
GO:0006886 TAS intracellular protein transport
GO:0022627 IDA cytosolic small ribosomal subunit
GO:0032790 IDA ribosome disassembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000012929 eif2d eukaryotic translation initiation factor 2D protein_coding Danio_rerio
ENSMUSG00000026427 Eif2d eukaryotic translation initiation factor 2D protein_coding Mus_musculus

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