C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tumor protein p53 binding protein 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000143514 TP53BP2 9606 - 1:223779899-223845972 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000343537 TP53BP2-001 223779899-223845972 protein_coding
  ENST00000391878 TP53BP2-002 223779899-223845930 protein_coding
  ENST00000464172 TP53BP2-011 223802301-223803223 retained_intron
  ENST00000464656 TP53BP2-014 223796174-223800726 nonsense_mediated_decay
  ENST00000465119 TP53BP2-008 223810464-223845954 nonsense_mediated_decay
  ENST00000472180 TP53BP2-003 223814176-223845794 processed_transcript
  ENST00000473135 TP53BP2-009 223806911-223826069 processed_transcript
  ENST00000481128 TP53BP2-006 223801939-223803330 processed_transcript
  ENST00000483398 TP53BP2-007 223780645-223800726 nonsense_mediated_decay
  ENST00000489310 TP53BP2-013 223799917-223802731 processed_transcript
  ENST00000490896 TP53BP2-012 223800776-223802657 retained_intron
  ENST00000494100 TP53BP2-010 223795838-223814328 protein_coding
  ENST00000496282 TP53BP2-004 223804235-223821136 processed_transcript
  ENST00000498843 TP53BP2-005 223780789-223802736 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000343537ENST00000391878ENST00000483398ENST00000489310ENST00000494100ENST00000498843
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000343537 3.467±0.00 6.333±0.00 0.376±0.00 6.398±3.80 2.097±0.38 2.256±0.05 1.151±0.75 0.473±0.00 0.622±0.00 4.047±2.68 3.740±0.00 4.502±1.37 2.814±1.30 3.432±1.40
ENST00000391878 1.299±0.00 1.251±0.00 0.480±0.00 2.295±0.00 1.131±0.42 0.850±0.00 0.962±0.32 2.415±0.00 0.351±0.00 0.638±0.00 N/A 1.238±0.00 0.823±0.18 1.284±0.00
ENST00000483398 N/A N/A N/A 7.058±0.00 N/A 1.410±0.00 N/A 2.219±1.18 0.778±0.00 N/A N/A 4.375±0.00 N/A 3.799±0.00
ENST00000489310 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.928±0.00 N/A N/A N/A
ENST00000494100 N/A N/A N/A N/A 4.117±0.00 N/A 1.216±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000498843 N/A N/A N/A 6.017±1.72 N/A 1.230±0.00 N/A N/A 0.959±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005070 TAS SH3/SH2 adaptor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0007049 IEA cell cycle
GO:0007165 TAS signal transduction
GO:0007417 IEA central nervous system development
GO:0007507 IEA heart development
GO:0009792 IEA embryo development ending in birth or egg hatching
GO:0009967 TAS positive regulation of signal transduction
GO:0010212 IEA response to ionizing radiation
GO:0017124 IEA SH3 domain binding
GO:0042802 IPI identical protein binding
GO:0045786 TAS negative regulation of cell cycle
GO:0048471 IDA perinuclear region of cytoplasm
GO:0051059 IPI NF-kappaB binding
GO:0072332 IDA intrinsic apoptotic signaling pathway by p53 class mediator

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000009136 tp53bp2 tumor protein p53 binding protein, 2 protein_coding Danio_rerio
ENSDARG00000054858 TP53BP2 (2 of 2) tumor protein p53 binding protein 2 protein_coding Danio_rerio
ENSMUSG00000026510 Trp53bp2 transformation related protein 53 binding protein 2 protein_coding Mus_musculus

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