C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: inositol-trisphosphate 3-kinase B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000143772 ITPKB 9606 - 1:226631690-226739323 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000272117 ITPKB-001 226631690-226737458 protein_coding
  ENST00000366784 ITPKB-002 226707190-226739323 protein_coding
  ENST00000429204 ITPKB-201 226631690-226739175 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000272117ENST00000366784ENST00000429204
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000272117 23.277±0.00 12.274±0.00 0.824±0.00 28.501±23.50 6.561±6.13 15.867±0.00 1.408±0.00 3.718±3.27 0.949±0.32 21.876±0.00 0.893±0.32 6.189±4.70 4.557±0.36 7.356±0.00
ENST00000366784 N/A 3.120±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 0.487±0.18 0.889±0.00 N/A N/A
ENST00000429204 6.553±0.00 N/A 2.299±0.00 9.449±0.00 1.275±0.85 1.894±0.46 2.705±1.29 2.200±1.86 3.348±2.91 7.098±5.06 N/A 2.712±1.33 4.248±2.27 2.858±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008CY CIL_0008CY_0001 VISTA 1:226526998-227129223
CIL_0000BV CIL_0000BV_0002 CGP 1:226548800-226739323
CIL_000985 CIL_000985_0001 VISTA 1:226618699-227222072

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000165 IEA MAPK cascade
GO:0005515 IPI protein binding
GO:0005516 IEA calmodulin binding
GO:0005524 IEA ATP binding
GO:0005829 TAS cytosol
GO:0007165 TAS signal transduction
GO:0007166 IEA cell surface receptor signaling pathway
GO:0008440 IEA inositol-1,4,5-trisphosphate 3-kinase activity
GO:0030217 IEA T cell differentiation
GO:0043647 TAS inositol phosphate metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045059 IEA positive thymic T cell selection
GO:0045061 IEA thymic T cell selection
GO:0046579 IEA positive regulation of Ras protein signal transduction
GO:0046638 IEA positive regulation of alpha-beta T cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010059 itpkb inositol-trisphosphate 3-kinase B protein_coding Danio_rerio
ENSMUSG00000038855 Itpkb inositol 1,4,5-trisphosphate 3-kinase B protein_coding Mus_musculus

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