C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: additional sex combs like transcriptional regulator 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000143970 ASXL2 9606 - 2:25733753-25878516 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000336112 ASXL2-201 25737692-25878466 protein_coding
  ENST00000404843 ASXL2-004 25741925-25780309 protein_coding
  ENST00000435504 ASXL2-001 25733753-25878516 protein_coding
  ENST00000497092 ASXL2-003 25768762-25830891 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000336112ENST00000404843ENST00000435504
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000336112 3.170±0.00 2.357±0.00 2.920±0.00 0.728±0.21 2.987±0.67 1.970±0.59 1.735±0.38 1.898±0.10 1.813±1.05 2.727±0.83 1.939±0.18 2.630±0.94 1.648±0.29 6.060±0.01
ENST00000404843 N/A N/A N/A N/A N/A N/A N/A 1.276±0.00 N/A N/A 1.277±0.00 N/A N/A 10.990±0.00
ENST00000435504 0.335±0.00 N/A 0.703±0.00 0.435±0.04 0.692±0.00 1.159±0.00 0.420±0.04 N/A 0.906±0.00 1.276±0.00 0.616±0.00 0.719±0.06 0.256±0.15 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003JK CIL_0003JK_0002 CGP 2:25377198-25878516
CIL_0003JN CIL_0003JN_0002 CGP 2:25733753-25982749

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000790 IEA nuclear chromatin
GO:0003677 IEA DNA binding
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007507 IEA heart development
GO:0007512 IEA adult heart development
GO:0035360 IDA positive regulation of peroxisome proliferator activated receptor signaling pathway
GO:0042975 IDA peroxisome proliferator activated receptor binding
GO:0045600 IDA positive regulation of fat cell differentiation
GO:0045672 IEA positive regulation of osteoclast differentiation
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0048704 IEA embryonic skeletal system morphogenesis
GO:1900159 IEA positive regulation of bone mineralization involved in bone maturation
GO:1902466 IEA positive regulation of histone H3-K27 trimethylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076501 asxl2 additional sex combs like 2 (Drosophila) protein_coding Danio_rerio
ENSMUSG00000037486 Asxl2 additional sex combs like 2 (Drosophila) protein_coding Mus_musculus

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