C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Meis homeobox 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000143995 MEIS1 9606 + 2:66433452-66573869 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000272369 MEIS1-001 66435400-66573869 protein_coding
  ENST00000398506 MEIS1-003 66437393-66573329 protein_coding
  ENST00000409517 MEIS1-013 66461798-66572454 processed_transcript
  ENST00000409622 MEIS1-010 66440097-66512191 processed_transcript
  ENST00000437869 MEIS1-006 66440678-66464220 protein_coding
  ENST00000450027 MEIS1-014 66508927-66568745 processed_transcript
  ENST00000466811 MEIS1-011 66440707-66454735 processed_transcript
  ENST00000475239 MEIS1-012 66445193-66567500 processed_transcript
  ENST00000488550 MEIS1-002 66435558-66572454 protein_coding
  ENST00000490726 MEIS1-005 66436917-66441440 processed_transcript
  ENST00000491706 MEIS1-008 66435169-66443772 retained_intron
  ENST00000495021 MEIS1-016 66439321-66572759 protein_coding
  ENST00000496248 MEIS1-009 66433452-66439967 processed_transcript
  ENST00000498705 MEIS1-007 66442775-66512294 retained_intron
  ENST00000542964 MEIS1-015 66496026-66571251 processed_transcript
  ENST00000560281 MEIS1-019 66435133-66568536 protein_coding
  ENST00000606455 MEIS1-018 66442965-66568714 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000272369ENST00000398506ENST00000409517ENST00000437869ENST00000488550ENST00000491706ENST00000495021ENST00000560281
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000272369 N/A N/A N/A N/A N/A N/A 0.590±0.00 0.551±0.00 N/A N/A N/A N/A N/A N/A
ENST00000398506 N/A N/A N/A N/A N/A N/A N/A 0.399±0.00 N/A N/A N/A 5.419±0.00 0.572±0.03 N/A
ENST00000409517 0.519±0.00 2.229±0.00 N/A 1.159±0.08 1.504±0.00 9.132±0.00 2.554±0.00 2.737±0.00 0.525±0.00 3.120±0.00 0.869±0.00 1.221±0.00 2.366±1.18 3.875±2.75
ENST00000437869 N/A N/A N/A N/A N/A N/A N/A 2.809±0.00 N/A N/A 1.583±0.00 N/A N/A N/A
ENST00000488550 0.276±0.00 0.703±0.00 1.230±0.00 0.518±0.11 1.948±1.34 1.867±0.18 0.639±0.00 N/A 4.734±0.00 1.976±1.24 0.170±0.00 2.888±1.94 0.468±0.18 0.745±0.38
ENST00000491706 N/A N/A 1.529±0.00 0.790±0.00 N/A N/A N/A N/A 11.898±0.00 N/A 0.666±0.00 3.572±0.00 5.442±0.00 N/A
ENST00000495021 0.809±0.00 1.208±0.00 N/A 1.289±0.00 1.714±0.57 5.831±2.03 1.683±0.68 N/A 2.744±2.22 2.213±0.44 0.234±0.00 10.526±9.49 2.166±0.35 3.321±2.00
ENST00000560281 0.337±0.00 0.582±0.00 1.967±0.00 0.886±0.24 3.285±0.00 N/A 1.670±0.00 0.363±0.00 8.280±0.00 4.305±0.00 0.551±0.00 3.819±2.19 N/A 0.548±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008ET CIL_0008ET_0001 VISTA 2:65870410-66471811
CIL_00085V CIL_00085V_0001 VISTA 2:65983424-66584663
CIL_0007JR CIL_0007JR_0003 UCNEbase 2:66138106-68180953
CIL_0008VO CIL_0008VO_0001 VISTA 2:66222407-66823799
CIL_000949 CIL_000949_0001 VISTA 2:66235383-66837956
CIL_00094L CIL_00094L_0001 VISTA 2:66397571-66998983

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001525 IEA angiogenesis
GO:0002089 IEA lens morphogenesis in camera-type eye
GO:0003677 IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0003705 IEA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005667 IEA transcription factor complex
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0030097 IEA hemopoiesis
GO:0035855 IEA megakaryocyte development
GO:0043565 IEA sequence-specific DNA binding
GO:0045638 ISS negative regulation of myeloid cell differentiation
GO:0045665 IEA negative regulation of neuron differentiation
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IEA protein heterodimerization activity
GO:0048514 IEA blood vessel morphogenesis
GO:0060216 IEA definitive hemopoiesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000020160 Meis1 Meis homeobox 1 protein_coding Mus_musculus

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