C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: endothelin converting enzyme 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000145194 ECE2 9606 + 3:184249650-184293031 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000324557 ECE2-002 184249650-184259585 protein_coding
  ENST00000357474 ECE2-006 184276035-184292350 protein_coding
  ENST00000359140 ECE2-004 184276011-184293031 protein_coding
  ENST00000402825 ECE2-001 184249695-184293031 protein_coding
  ENST00000404464 ECE2-003 184276016-184293031 protein_coding
  ENST00000422932 ECE2-009 184276154-184278173 nonsense_mediated_decay
  ENST00000430587 ECE2-007 184276604-184291930 protein_coding
  ENST00000462596 ECE2-011 184278215-184278908 retained_intron
  ENST00000474750 ECE2-010 184276160-184277343 retained_intron
  ENST00000488401 ECE2-005 184276028-184292065 retained_intron
  ENST00000490579 ECE2-008 184276930-184291217 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000324557ENST00000357474ENST00000359140ENST00000402825ENST00000404464ENST00000430587ENST00000490579
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000324557 1.497±0.00 1.029±0.00 0.130±0.00 N/A 0.484±0.33 0.508±0.20 0.212±0.12 1.943±1.11 6.831±0.00 0.723±0.51 2.557±0.00 4.708±4.70 5.331±1.72 6.312±0.83
ENST00000357474 N/A N/A N/A N/A N/A 0.581±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000359140 N/A N/A N/A 0.386±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000402825 N/A N/A N/A N/A N/A 0.472±0.00 N/A N/A N/A N/A N/A N/A N/A 0.451±0.00
ENST00000404464 N/A N/A N/A 2.580±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000430587 N/A N/A N/A 0.329±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000490579 N/A N/A N/A N/A N/A N/A N/A N/A 0.029±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005G3 CIL_0005G3_0001 CGP 3:184135038-184684758
CIL_000573 CIL_000573_0001 CGP 3:184242301-184293031
CIL_000574 CIL_000574_0001 CGP 3:184249650-184293031

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004222 IDA metalloendopeptidase activity
GO:0005794 IEA Golgi apparatus
GO:0006508 IEA proteolysis
GO:0007267 TAS cell-cell signaling
GO:0007420 ISS brain development
GO:0007507 ISS heart development
GO:0008152 IEA metabolic process
GO:0008168 IEA methyltransferase activity
GO:0010002 ISS cardioblast differentiation
GO:0016021 IEA integral component of membrane
GO:0016486 IDA peptide hormone processing
GO:0030659 IDA cytoplasmic vesicle membrane
GO:0032259 IEA methylation
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000087841 ECE2 endothelin converting enzyme 2 protein_coding Danio_rerio
ENSMUSG00000022842 Ece2 endothelin converting enzyme 2 protein_coding Mus_musculus

Loading