C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: corin, serine peptidase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000145244 CORIN 9606 - 4:47593998-47838106 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000273857 CORIN-001 47593998-47837949 protein_coding
  ENST00000502252 CORIN-005 47595660-47838072 protein_coding
  ENST00000502726 CORIN-006 47679531-47838106 retained_intron
  ENST00000503821 CORIN-004 47661488-47838067 retained_intron
  ENST00000504584 CORIN-010 47642843-47838106 protein_coding
  ENST00000505754 CORIN-002 47642841-47661860 retained_intron
  ENST00000505909 CORIN-003 47595721-47837949 protein_coding
  ENST00000508498 CORIN-009 47595482-47790260 protein_coding
  ENST00000510974 CORIN-011 47786724-47837507 processed_transcript
  ENST00000515827 CORIN-013 47623584-47632452 processed_transcript
  ENST00000610355 CORIN-201 47593999-47838106 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000273857ENST00000502252ENST00000502726ENST00000503821ENST00000504584ENST00000505754ENST00000508498ENST00000510974ENST00000515827ENST00000610355
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000273857 0.036±0.00 N/A 0.015±0.00 0.358±0.24 N/A 6.986±5.72 0.813±0.00 N/A N/A N/A 0.294±0.14 0.038±0.00 0.568±0.03
ENST00000502252 N/A N/A 0.037±0.00 N/A N/A 3.986±1.79 0.044±0.00 N/A 0.213±0.00 N/A 0.382±0.00 N/A N/A
ENST00000502726 0.052±0.00 0.060±0.00 0.062±0.00 0.154±0.08 0.045±0.00 1.581±0.00 N/A 0.012±0.00 0.136±0.00 N/A 0.021±0.00 N/A N/A
ENST00000503821 N/A N/A N/A N/A N/A N/A 0.085±0.00 N/A N/A N/A N/A 0.057±0.00 N/A
ENST00000504584 N/A N/A 0.316±0.00 N/A N/A 5.128±0.00 N/A 0.038±0.00 N/A N/A N/A 0.119±0.07 0.767±0.00
ENST00000505754 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.410±0.14 N/A
ENST00000508498 N/A N/A N/A N/A 0.119±0.00 N/A N/A N/A N/A N/A 0.440±0.00 N/A 0.737±0.35
ENST00000510974 0.379±0.00 N/A N/A N/A N/A N/A N/A 0.400±0.00 N/A N/A N/A N/A N/A
ENST00000515827 N/A N/A N/A 1.674±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000610355 N/A 0.056±0.00 0.060±0.00 0.415±0.00 0.153±0.00 N/A 0.255±0.00 N/A N/A 0.009±0.00 0.435±0.14 N/A 0.320±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008RD CIL_0008RD_0001 VISTA 4:47524449-48126035
CIL_0001MZ CIL_0001MZ_0001 CGP 4:47593998-47914667

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003050 ISS regulation of systemic arterial blood pressure by atrial natriuretic peptide
GO:0003824 IEA catalytic activity
GO:0004252 IEA:IDA serine-type endopeptidase activity
GO:0005515 IEA protein binding
GO:0005576 IEA extracellular region
GO:0005886 IEA plasma membrane
GO:0005887 IDA integral component of plasma membrane
GO:0006508 IEA proteolysis
GO:0007565 IMP female pregnancy
GO:0008217 ISS regulation of blood pressure
GO:0009986 IEA cell surface
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016486 IDA peptide hormone processing
GO:0035813 ISS regulation of renal sodium excretion
GO:0070008 IEA serine-type exopeptidase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076412 CORIN corin, serine peptidase protein_coding Danio_rerio
ENSMUSG00000005220 Corin corin protein_coding Mus_musculus

Loading