C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ubiquitin specific peptidase 53
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000145390 USP53 9606 + 4:119212587-119295517 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000274030 USP53-001 119212636-119294746 protein_coding
  ENST00000450251 USP53-201 119239216-119295517 protein_coding
  ENST00000507597 USP53-007 119212741-119239341 processed_transcript
  ENST00000507906 USP53-008 119261793-119271353 nonsense_mediated_decay
  ENST00000509769 USP53-003 119239640-119294638 nonsense_mediated_decay
  ENST00000510737 USP53-006 119213179-119239312 processed_transcript
  ENST00000510852 USP53-004 119267381-119273330 retained_intron
  ENST00000514305 USP53-005 119212743-119220211 processed_transcript
  ENST00000514665 USP53-002 119212587-119221495 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000274030ENST00000450251ENST00000509769ENST00000514305ENST00000514665
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000274030 N/A N/A N/A N/A N/A N/A 1.372±0.70 N/A 1.955±0.00 2.479±0.00 N/A 1.583±0.00 0.286±0.00 N/A
ENST00000450251 8.014±0.00 2.992±0.00 1.703±0.00 1.485±0.22 3.643±1.89 4.027±0.06 4.561±1.33 5.682±0.00 1.726±0.91 8.887±2.77 5.671±0.00 1.597±0.28 1.075±0.50 2.313±0.54
ENST00000509769 3.964±0.00 2.311±0.00 N/A 1.685±0.32 3.162±1.53 3.786±0.62 2.475±1.29 3.183±1.99 0.517±0.00 5.385±0.00 2.712±0.52 1.490±0.43 2.071±1.73 2.538±0.75
ENST00000514305 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 8.750±0.00 N/A 9.818±0.00
ENST00000514665 N/A N/A 2.657±0.00 N/A N/A 2.843±0.00 1.177±0.00 N/A 3.412±0.00 4.707±0.00 N/A 1.223±0.33 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005575 ND cellular_component
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0008150 ND biological_process
GO:0036459 IEA ubiquitinyl hydrolase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076499 usp53b ubiquitin specific peptidase 53b protein_coding Danio_rerio
ENSDARG00000078615 USP53 (2 of 2) ubiquitin specific peptidase 53 protein_coding Danio_rerio
ENSMUSG00000039701 Usp53 ubiquitin specific peptidase 53 protein_coding Mus_musculus

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