C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: betaine--homocysteine S-methyltransferase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000145692 BHMT 9606 + 5:79111779-79132290 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000274353 BHMT-001 79111779-79132290 protein_coding
  ENST00000520335 BHMT-004 79111809-79116404 retained_intron
  ENST00000520703 BHMT-005 79111809-79119606 retained_intron
  ENST00000521279 BHMT-006 79121281-79128197 retained_intron
  ENST00000523508 BHMT-007 79120352-79126297 retained_intron
  ENST00000524080 BHMT-003 79111809-79131484 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonKidneyLiverLungMuscleTestisENST00000274353ENST00000521279
Transcript ID Bladder Brain Breast Colon Kidney Liver Lung Muscle Testis
ENST00000274353 54.637±0.00 0.135±0.00 0.321±0.00 0.235±0.00 72.877±29.35 15.611±13.70 0.173±0.00 N/A 0.324±0.00
ENST00000521279 N/A N/A N/A N/A N/A N/A N/A 1.269±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000096 TAS sulfur amino acid metabolic process
GO:0005737 IDA:IEA cytoplasm
GO:0005829 TAS cytosol
GO:0006479 NAS protein methylation
GO:0006577 IDA amino-acid betaine metabolic process
GO:0006579 IEA amino-acid betaine catabolic process
GO:0008168 IEA methyltransferase activity
GO:0008270 IDA:IEA zinc ion binding
GO:0008898 IEA S-adenosylmethionine-homocysteine S-methyltransferase activity
GO:0009086 IEA methionine biosynthetic process
GO:0010243 IEA response to organonitrogen compound
GO:0032259 IEA methylation
GO:0032403 IEA protein complex binding
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0043234 IEA protein complex
GO:0044281 TAS small molecule metabolic process
GO:0047150 NAS:IEA betaine-homocysteine S-methyltransferase activity
GO:0050666 NAS regulation of homocysteine metabolic process
GO:0070062 IDA extracellular vesicular exosome
GO:0071267 IDA L-methionine salvage

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013430 bhmt betaine-homocysteine methyltransferase protein_coding Danio_rerio
ENSMUSG00000069324 Gm5096 predicted gene 5096 protein_coding Mus_musculus
ENSMUSG00000074768 Bhmt betaine-homocysteine methyltransferase protein_coding Mus_musculus

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