C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000146070 PLA2G7 9606 - 6:46704201-46735693 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000274793 PLA2G7-001 46704201-46735342 protein_coding
  ENST00000537365 PLA2G7-201 46704317-46735693 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartLiverLungOvaryPlacentaENST00000274793ENST00000537365
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Liver Lung Ovary Placenta
ENST00000274793 0.663±0.00 1.367±0.00 N/A 0.646±0.00 0.713±0.00 N/A N/A N/A 0.608±0.00 0.703±0.00 4.895±3.41
ENST00000537365 2.369±0.00 1.954±0.00 0.144±0.00 0.442±0.00 2.066±0.00 0.714±0.01 0.282±0.00 0.646±0.11 2.422±0.11 2.593±1.43 6.919±5.90

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000087 CIL_000087_0002 CGP 6:46687875-46735693
CIL_0008BB CIL_0008BB_0001 VISTA 6:46689530-47290187

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003847 IEA 1-alkyl-2-acetylglycerophosphocholine esterase activity
GO:0005543 IDA phospholipid binding
GO:0005576 TAS extracellular region
GO:0005615 IEA extracellular space
GO:0005737 IEA cytoplasm
GO:0016042 IEA lipid catabolic process
GO:0034362 IDA low-density lipoprotein particle
GO:0034374 IDA low-density lipoprotein particle remodeling
GO:0034440 IDA lipid oxidation
GO:0034441 IDA plasma lipoprotein particle oxidation
GO:0044267 TAS cellular protein metabolic process
GO:0047499 IDA calcium-independent phospholipase A2 activity
GO:0050729 TAS positive regulation of inflammatory response
GO:0090026 IDA positive regulation of monocyte chemotaxis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003584 pla2g7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) protein_coding Danio_rerio
ENSMUSG00000023913 Pla2g7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) protein_coding Mus_musculus

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