C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tumor necrosis factor receptor superfamily, member 21
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000146072 TNFRSF21 9606 - 6:47231532-47309905 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000296861 TNFRSF21-001 47231532-47309905 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000296861
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000296861 10.375±0.00 7.786±0.00 4.845±0.00 12.290±9.05 25.192±0.00 7.147±3.97 2.656±1.92 9.472±8.46 2.353±0.54 8.596±7.89 1.359±0.42 9.722±6.65 23.524±4.21 4.806±0.62

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008BB CIL_0008BB_0001 VISTA 6:46689530-47290187
CIL_000082 CIL_000082_0002 CGP 6:46997703-47309905
CIL_00007L CIL_00007L_0002 CGP 6:47231532-47627263

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001783 ISS B cell apoptotic process
GO:0002250 ISS adaptive immune response
GO:0005515 IPI:IEA protein binding
GO:0005886 TAS plasma membrane
GO:0005887 IDA integral component of plasma membrane
GO:0006915 IMP apoptotic process
GO:0006959 ISS humoral immune response
GO:0007165 IEA signal transduction
GO:0030424 IEA axon
GO:0030889 ISS negative regulation of B cell proliferation
GO:0031226 ISS intrinsic component of plasma membrane
GO:0031642 IMP negative regulation of myelination
GO:0042130 ISS negative regulation of T cell proliferation
GO:0042552 ISS myelination
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0048713 ISS regulation of oligodendrocyte differentiation
GO:0050852 ISS T cell receptor signaling pathway
GO:0051402 ISS neuron apoptotic process
GO:0071356 IDA cellular response to tumor necrosis factor
GO:0097252 ISS oligodendrocyte apoptotic process
GO:2000663 ISS negative regulation of interleukin-5 secretion
GO:2000666 ISS negative regulation of interleukin-13 secretion
GO:2001180 ISS negative regulation of interleukin-10 secretion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000001807 tnfrsf21 tumor necrosis factor receptor superfamily, member 21 protein_coding Danio_rerio
ENSMUSG00000023915 Tnfrsf21 tumor necrosis factor receptor superfamily, member 21 protein_coding Mus_musculus

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